Biliary Atresia
Also covered as: cholestasis · cirrhosis · cholangitis · portal hypertension · jaundice · ascites · Alagille syndrome · alpha-1 antitrypsin deficiency
Educational content from recorded physician discussions — not medical advice. Always talk to your child's care team about your child's situation.
Answers come only from this collection's statement ledger and cite the exact moment · not medical advice
Content of this collection
Foundations
3 items
Biliary Atresia: Where are we now? Advanced Practice Providers Pediatric...
Watch →
At the Advanced Practice Providers Pediatric Surgery Update Course in 2014, many distinguished advanced practice providers from around the world address the current evidence based management of the common pediatric surgical conditions. The
video · 48:21 · Jan 2019
Choledochal Cyst Podcast
Listen →
In this podcast, Dr. Alex Bondoc and Dr. Rae Hanke discuss the intricacies of choledochal cysts. Contributing editor: Dr. Rod Gerardo.Choledochal Cyst- Definition: Congenital cystic dilation of the biliary tree- Epidemiology: We
podcast · 22:07 · Dec 2020
Biliary Atresia with Dr. Greg Tiao
Watch →
Check out this week's episode with everything the surgical trainee needs to know about the work up, management, and types of biliary atresia with Dr. Greg Tiao from Cincinnati Children's Hospital.
video · 11:34 · Jun 2022
Diagnosis & Workup
3 items
Biliary Atresia Part I
Listen →
This podcast is a discussion of the international approach to diagnosis and management of biliary atresia, amongst Dr. Todd Ponsky, Dr. Yamataka Atsuyuki, Dr. Greg Tiao, Dr. Mark Davenport, and Dr. Jorge Bezerra.
In part one of this podcas
podcast · 31:15 · Oct 2022
BOB Ped Surg 2023 - Maria Soledad Jara Valdivia, CIPESUR - Presentation
Watch →
Watch Maria Soledad Jara Valdivia, MD, present her presentation on "The immunohistochemical staining CD56 is useful in the diagnosis of biliary atresia."
video · Feb 2023
Update Course Rewind: MMP-7 & Biliary Atresia Diagnosis 2024
Watch →
In this Update Course Rewind session, Dr. Greg Tiao, Surgical Director of the Liver Transplantation Program at Cincinnati Children’s, discusses the critical role of MMP-7 as a biomarker in the early diagnosis of biliary atresia. With data s
video · 6:24 · Mar 2025
Medical Management
1 item
Biliary Atresia Part II
Listen →
This podcast is a discussion of the international approach to diagnosis and management of biliary atresia, amongst Dr. Todd Ponsky, Dr. Yamataka Atsuyuki, Dr. Greg Tiao, Dr. Mark Davenport, and Dr. Jorge Bezerra. In part two of this podcast
podcast · 42:23 · Oct 2022
Surgical Management
3 items
Biliary Atresia: Update Course 2015
Watch →
During the 3rd Annual Stay Current in Pediatric Surgery Update Course in 2015, Dr. Greg M. Tiao, Chief of Pediatric Surgery at Cincinnati Children's Hospital, discusses biliary atresia. Dr. Tiao covers topics on cholestasis in infants, diag
video · 20:34 · Jan 2019
Error Traps and Culture of Safety in Biliary Atresia
Watch →
This video highlights a few key points from the "Error Traps and Culture of Safety in Biliary Atresia" article published in Seminars in Pediatric Surgery, provided by lead author Dr. Jonathan Roach. Find the full article at: www.sciencedire
video · 4:32 · Nov 2019
Heat 1 Winner: Dariusz Patkowski, MD, PhD - Best of the Best in Pediatric Surgery 2024
Watch →
Watch the voting from the first heat!
Presentations from heat one:
Prof. Shilpa Sharma: Exploring alternative pathway of stem cell proliferation for hepatic regeneration by partial liver resection in extra hepatic biliary atresia.
video · 2:30 · Feb 2024
Evidence & Research
11 items
Biliary Atresia, Appendicitis, Intestinal Failure, and Anesthetic...
Listen →
Audio Journal with Dr. Von Allmen about usingCorticosteroids After Hepatoportoenterostomy for Bile Drainage, Dr. Whit Holcomb aboutsurgical site infections (SSI) are an important source of morbidity and mortality.andfeasibility and safety o
podcast · 44:19 · Jan 2019
Biliary Atresia, Appendicitis, Intestinal Failure, and Anesthetic...
Listen →
Audio Journal with Dr. Von Allmen about using Corticosteroids After Hepatoportoenterostomy for Bile Drainage, Dr. Whit Holcomb about surgical site infections (SSI) are an important source of morbidity and mortality. and feasibility and safe
podcast · 44:19 · Dec 2020
Update Course 2021: UPDATE COURSE 2020: REVIEW OF LAST YEAR'S IMPORTANT T OPICS
Watch →
General surgery residentRodrigo Gerardo, MD reviews the highlights from the 2020 Update Course including MMP7 for diagnosing biliary atresia, complex gastroschisis, and so much more.
video · 23:20 · May 2022
Quick Literature Updates Episode 9
Watch →
We’re back with ninth episode of "Quick Literature Updates" the podcast series that delivers the latest updates in pediatric surgery literature in a quick and digestible format. In each episode, we review four articles covering the most int
video · Jun 2023
Heat 3 Winner: Shruthi Srinivas, MD - Best of the Best in Pediatric Surgery 2024
Watch →
Watch the voting from the third heat!
Presentations from heat three:
Mina Yeganeh, BSc: Lipid nanoparticle delivery of miRNA-148a attenuates intestinal inflammation during experimental.
Joseph Davidson, MA(Oxon), MBBS, MRCS(Eng)
video · 1:47 · Feb 2024
Jingying Jiang, MD - Best of the Best in Pediatric Surgery 2024
Watch →
Watch PAPS' Dr. Jingying Jiang’s presentation on “Clinical characteristics and prognosis of biliary atresia with low serum matrix metalloproteinase-7 levels.” at the 2024 Best of the Best in Pediatric Surgery event!
Moderators: Todd Pons
video · 6:58 · Feb 2024
Clinical Characteristics and Prognosis of Biliary Atresia with Low Serum Matrix Metalloproteinase-7 Levels
Watch →
New Article you should know by Dr. Cecilia Gigena from Journal of Pediatric Surgery.
"Clinical Characteristics and Prognosis of Biliary Atresia with Low Serum Matrix Metalloproteinase-7 Levels"
Authors: Jingying Jiang, Yifan Yang, Xue
video · 0:55 · Jul 2024
Características clínicas y pronóstico de la atresia de vías biliares con niveles bajos de metaloproteinasa 7 de la matriz sérica
Watch →
Nuevo artículo que tienes que conocer por la Dra. Cecilia Gigena del JPS
"Características clínicas y pronóstico de la atresia de vías biliares con niveles bajos de metaloproteinasa 7 de la matriz sérica"
Autores: Jingying Jiang, Yifa
video · 0:55 · Jul 2024
Journal of Pediatric Surgery Article Review: 2nd Quarter (Apr-Jun) 2024
Listen →
We are back with another episode of our Journal of Pediatric Surgery article review podcast. This time we have three publications from the second quarter of 2024, April, May, and June issues. This time we're talking to editors Drs. Mary Bri
podcast · 17:03 · Sep 2024
Update Course Rewind: 2024 Top Ten Key Takeaways
Watch →
Join us for a highlight reel of the Top 10 Key Takeaways from the 12th Annual Update Course in Pediatric Surgery. This session covers the latest advances, practical tools, and emerging trends that are shaping the future of pediatric surgica
video · 18:01 · Jun 2025
Update Course Rewind: 2024 Top Ten Key Takeaways
Listen →
Update Course Rewind: 2024 Top Ten Key Takeaways | Podcast Episode on RSS.com Sign up free Features Resources Pricing Podcasts Sign up free Sign In Stay Current in Pediatric Surgery... Update Course Rewind: 2024 Top Te... Update Course Rewi
podcast · 18:01 · Jul 2026
Case-Based Learning
3 items
Biliary Atresia - Robert Parry: Update Course 2014
Watch →
Dr. Robert Parry, Director of Pediatric Surgery, Akron Children's Hospital, presents a clinical case of biliary atresia diagnosis. Topics discussed include kasai procedure, HIDA scan for biliary atresia, postoperative corticosteroids, and r
video · 24:55 · Nov 2018
Biliary Atresia-Case Presentation and Panel Discussion: Update Course 2014
Watch →
During the 2ndAnnual Stay Current in Pediatric Surgery Update Course in 2014, Dr. Robert Parry, Director of Pediatric Surgery, Akron Children's Hospital, and Dr. Nick Bruns present a clinical case of biliary atresia diagnosis. Topics discus
video · 23:47 · Jan 2019
Biliary Atresia - Clinical Practice Updates
Watch →
This clip from the 2020 Pediatric Surgery Update Course features Alexander Bondoc, MD, presenting multiple cases and research conclusions from Atsuyuki Yamataka, MD; Greg Tiao, MD; Jorge Bezerra, MD; and Mark Davenport, MD, to our selected
video · Sep 2020
In-Depth Reviews
1 item
Biliary Atresia
Watch →
Dr. Greg M. Tiao, Chief of Pediatric Surgery at Cincinnati Children's Hospital, discusses biliary atresia. Dr. Tiao covers topics on cholestasis in infants, diagnosis imaging in cholestatic infant, liver biopsy, biliary atresia extended dis
video · 20:57 · Jan 2019
Emerging & Future Directions
1 item
Prof. Shilpa Sharma - Best of the Best in Pediatric Surgery 2024
Watch →
Watch WOFAPS' Prof. Shilpa Sharma's presentation on "Exploring alternative pathway of stem cell proliferation for hepatic regeneration by partial liver resection in extra hepatic biliary atresia" at the 2024 Best of the Best in Pediatric Su
video · 5:46 · Feb 2024
Share & build on it
Want more on this topic?+ Show
The story of this collection+ Show
Featured chapters & key critical points+ Show
Featured picks for families are being prepared — the summaries above are written for you.
What we know now+ Show
The doctors+ Show
Inside the topic+ Show
Every statement below comes from the recorded discussions, with its speaker and moment.
Biliary Atresia
Idiopathic neonatal hepatitis has decreased from approximately 70% of cholestatic infants in the 1970s-1980s to approximately 10% currently due to improved recognition of specific etiologies
epidemiological1:42 ↗
The jaundice chip microarray takes 4-6 weeks to return results, too long to guide initial biliary atresia management decisions
clinical3:42 ↗
Absence of gallbladder on ultrasound does not conclusively diagnose biliary atresia
clinical4:51 ↗
Presence of a gallbladder does not exclude biliary atresia because modern ultrasound can visualize small shrunken gallbladders
clinical4:57 ↗
HIDA scan requires 3-5 days of phenobarbital loading, which can delay intervention into a time period potentially detrimental to Kasai outcomes
clinical6:03 ↗
Cincinnati Children's Hospital does not routinely use HIDA scans for biliary atresia workup
clinical6:00 ↗
Interventional radiologists at Cincinnati perform percutaneous liver biopsies in infants as young as 3-4 weeks without complications
clinical7:39 ↗
Pathognomonic biopsy findings for biliary atresia include bile duct proliferation in portal triads and bile plugs within bile ducts
clinical8:23 ↗
When bile plugs are seen on biopsy, the likelihood of biliary atresia is well over 90%
clinical8:34 ↗
Alagille syndrome patients do not have the same bile duct proliferation or bile duct plugs seen in biliary atresia
clinical10:28 ↗
Extended Kasai dissection goes beyond portal vein bifurcation to the first bifurcation of hepatic arteries, as originally described by Kasai
clinical12:26 ↗
Japanese centers may have better Kasai outcomes because they perform more extended dissections uniformly
opinion12:35 ↗
Polysplenia syndrome patients with pre-duodenal portal veins are most difficult for Kasai because there is often no bile duct remnant and bile ducts are all above the portal vein
clinical13:44 ↗
Mark Davenport's data from England shows cystic variant biliary atresia patients have better outcomes if intervention occurs before 30 days of age
clinical14:57 ↗
Choledochal cyst patients have pigmented stool while cystic variant biliary atresia patients become acholic
clinical15:14 ↗
A 20 cm Roux limb is inadequate because 5-8 cm of length is typically lost during hilar dissection at the time of liver transplantation
clinical15:47 ↗
Target Roux limb length should be 30-40 cm to preserve adequate length for future transplantation
clinical16:09 ↗
Anti-refluxing valves for Kasai have not been proven effective
clinical16:32 ↗
UK data shows centers performing more than 5 Kasai cases per year have much better outcomes than those performing fewer, with approximately 20% difference
epidemiological17:35 ↗
British health services centralized all Kasai procedures to three high-volume centers based on outcome data
clinical17:38 ↗
King's College group used low-dose steroids at 2 mg/kg and showed no benefit
clinical18:03 ↗
Klaus Peterson's German group used 10 mg/kg steroids for 5 days and showed no benefit
clinical18:17 ↗
The Children's Network START trial enrolled approximately 70 patients in two arms and showed no improvement in bile drainage with corticosteroids
clinical18:29 ↗
The START trial showed a slight increase in adverse events in patients who received steroids, though these were medical rather than surgical complications
clinical18:42 ↗
A subset of biliary atresia patients have an inflammatory gene profile in which steroids might prove beneficial despite negative trial results
opinion18:57 ↗
Cincinnati does not use MRCP for biliary atresia diagnosis because they have high-capacity pathology teams
clinical19:39 ↗
Performing Kasai on Alagille syndrome patients will shorten their natural history and lead to earlier transplantation
clinical20:12 ↗
For cholestatic infants where biliary atresia diagnosis is uncertain, workup includes echocardiography for pulmonic stenosis, spine X-rays for butterfly vertebrae, and ophthalmologic examination to evaluate for Alagille syndrome
clinical20:21 ↗
Biliary Atresia-Case Presentation and Panel Discussion: Update Course 2014
French registry data show significantly better 5- and 10-year native liver survival when Kasai performed before 30 days versus after 90 days, with nearly twice the survival rate
clinical2:44 ↗
In a Michigan series, children who had Kasai after 3 months had the best drainage and long-term outcomes
clinical1:03 ↗