Jill Knepprath

184 timestamped statements across 10 collections — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Abdominal Wall Defects · episode host Aerodigestive / ENT · episode host Colorectal / ARM & Hirschsprung · series host Fetal Surgery · episode host Inguinal Hernia · episode host Liver Tumors (Hepatoblastoma/HCC) · episode host Neurofibromatosis · episode host Pediatric Robotic Surgery · episode host Peritoneal Dialysis Access · episode host Wilms Tumor · episode host

Featured diaries

▶ Ep 19 · 1:04
One cue gain is the superior prognostic factor when compared to size and number of nodules in patients with favorable histology Wilms and pulmonary metastases.
quote · Wilms Tumor
▶ Ep 1 · 1:03
Overall, this study confirms that resection should be done for these patients whenever possible, even if they show a good response to chemo radiation.
quote · Neurofibromatosis
▶ Ep 16 · 0:52
The authors think that blood transfusions were mostly red blood cells, and that is what contributed to the post-op coagulopathy.
quote · Liver Tumors (Hepatoblastoma/HCC)
▶ Ep 47 · 0:22
The authors found that inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence.
quote · Abdominal Wall Defects
▶ Ep 28 · 0:22
The authors found that inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence.
quote · Aerodigestive / ENT
▶ Ep 22 · 0:22
The authors found that inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence.
quote · Inguinal Hernia

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Abdominal Wall Defects 7 entries

Surgeon annual volume impacts recurrence rates of pediatric inguinal hernia repairs: A multi-institutional study

▶ Ep 47 · 0:10
epidemiological Heller et al. published a multi-institutional study in the Journal of Pediatric Surgery in 2025 ↗
▶ Ep 47 · 0:22
quote The authors found that inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence. ↗
▶ Ep 47 · 0:22
epidemiological Inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence ↗
▶ Ep 47 · 0:30
epidemiological There was no difference in recurrence rates for open repairs based on surgeon volume ↗
▶ Ep 47 · 0:35
quote However, laparoscopic repairs done by lower volume surgeons had a 3.3 fold increase in the odds of recurrence. ↗
▶ Ep 47 · 0:35
epidemiological Laparoscopic repairs done by lower volume surgeons had a 3.3 fold increase in the odds of recurrence ↗
▶ Ep 47 · 0:44
guideline The authors recommend maintaining a high volume of laparoscopic repairs, and if that's not possible, to seek help from a higher volume surgeon ↗
Aerodigestive / ENT 7 entries

Surgeon annual volume impacts recurrence rates of pediatric inguinal hernia repairs: A multi-institutional study

▶ Ep 28 · 0:10
epidemiological Heller et al. published a multi-institutional study in the Journal of Pediatric Surgery in 2025 ↗
▶ Ep 28 · 0:22
epidemiological Inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence ↗
▶ Ep 28 · 0:22
quote The authors found that inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence. ↗
▶ Ep 28 · 0:30
epidemiological There was no difference in recurrence rates for open repairs based on surgeon volume ↗
▶ Ep 28 · 0:35
quote However, laparoscopic repairs done by lower volume surgeons had a 3.3 fold increase in the odds of recurrence. ↗
▶ Ep 28 · 0:35
epidemiological Laparoscopic repairs done by lower volume surgeons had a 3.3 fold increase in the odds of recurrence ↗
▶ Ep 28 · 0:44
guideline The authors recommend maintaining a high volume of laparoscopic repairs, and if that's not possible, to seek help from a higher volume surgeon ↗
Colorectal / ARM & Hirschsprung 78 entries

Patient-reported outcomes of Children with an Anorectal Malformation

▶ Ep 187 · 0:02
quote Are you using the sacral ratio to counsel them? ↗
▶ Ep 187 · 0:10
clinical A 2024 survey by Witt et al. at Nationwide Children's was published in the Annals of Surgery examining patients with anorectal malformation ↗
▶ Ep 187 · 0:11
epidemiological The survey looked at over 900 patients with anorectal malformation ↗
▶ Ep 187 · 0:21
clinical There was no difference in continence for patients based on sacral ratio alone in regards to quality of life ↗
▶ Ep 187 · 0:29
clinical Patients who are incontinent had a 20-point lower quality of life compared to patients who were continent or clean on enemas ↗
▶ Ep 187 · 0:38
opinion Bowel management may actually matter more than sacral ratio in predicting continence outcomes ↗
▶ Ep 187 · 0:38
opinion The sacral ratio may not be as strong a predictor of continence as patients age ↗
▶ Ep 187 · 0:51
clinical Quality of life is significantly lower for patients with incontinence compared to those clean on enemas ↗
▶ Ep 187 · 0:57
quote Does this change this change your practice? ↗

Update Course Rewind 2025: Timing of PSARP: Early vs. Delayed—Does It Really Matter?

▶ Ep 194 · 1:49
clinical It's safe to perform the PSARP either early before discharge or later around 1 to 3 months of age ↗
▶ Ep 194 · 2:00
epidemiological NSQIP study defined early repair as 7 days and delayed repair as between 6 weeks and 8 months ↗
▶ Ep 194 · 2:07
epidemiological NSQIP study found no difference in overall outcomes including re-operations and readmissions between early and delayed PSARP ↗
▶ Ep 194 · 2:26
epidemiological Wound breakdown and dehiscence was the most common complication for both early and delayed repair groups ↗
▶ Ep 194 · 2:33
epidemiological No significant difference in postoperative complications between early and delayed PSARP groups ↗
▶ Ep 194 · 3:07
clinical Early repair during newborn period avoids an additional admission for the surgery ↗
▶ Ep 194 · 3:23
clinical Both early and delayed PSARP repairs are safe for patients with rectal vestibular fistulas ↗
▶ Ep 194 · 3:29
opinion What matters most for timing is the circumstances, family access to care, patient size, and surgeon comfort and experience ↗

Update Course Rewind 2025: Perineal Body–Preserving PSARP: The New Standard?

▶ Ep 195 · 1:01
quote 2/3 of the patients went home on postoperative day one. ↗
▶ Ep 195 · 1:01
clinical Two-thirds of patients went home on postoperative day one after perineal body-preserving PSARP ↗
▶ Ep 195 · 1:51
opinion Perineal body-preserving PSARP can be a trickier approach than standard PSARP ↗
▶ Ep 195 · 2:00
guideline Conversion to standard approach is a valid pivot when in doubt about anatomy ↗

Laparoscopic modified percutaneous internal ring suturing - a mesh-free alternative for indirect inguinal hernia repair in adults. a pilot prospective cohort study

▶ Ep 196 · 0:00
quote High ligation hernia repair, that's for kids. ↗
▶ Ep 196 · 0:00
clinical High ligation hernia repair is traditionally a pediatric technique ↗
▶ Ep 196 · 0:03
quote Or is it? ↗
▶ Ep 196 · 0:08
clinical The study was published in the International Journal of Surgery ↗
▶ Ep 196 · 0:12
clinical The study used modified percutaneous internal ring suturing technique for laparoscopic non-mesh repair of indirect inguinal hernias in adults ↗
▶ Ep 196 · 0:23
epidemiological The study included 20 patients ↗
▶ Ep 196 · 0:25
epidemiological The majority of patients were male ↗
▶ Ep 196 · 0:26
clinical No patients had hernia recurrence on follow-up ↗
▶ Ep 196 · 0:26
epidemiological Median follow-up duration was 79 months ↗
▶ Ep 196 · 0:31
clinical Patients reported improved activity postoperatively ↗
▶ Ep 196 · 0:31
clinical Patients reported a decrease in pain postoperatively ↗
▶ Ep 196 · 0:35
opinion This is a small single-center study ↗
▶ Ep 196 · 0:35
opinion The study shows success with this technique in adults ↗
▶ Ep 196 · 0:41
quote Would you offer this to your hernia patients? ↗

Update Course Rewind 2025: Do We Still Need Routine Anal Dilations After PSARP?

▶ Ep 197 · 0:21
clinical For decades, every child received anal dilations after PSARP ↗
▶ Ep 197 · 0:40
clinical Spanish study followed historical dilation protocol starting two weeks after PSARP ↗
▶ Ep 197 · 0:45
clinical Spanish protocol involved dilations twice daily with Hagar size increased by 1 millimeter each week until optimal size reached ↗
▶ Ep 197 · 1:12
clinical Heineke-Mikulicz anoplasty is a procedure for skin-level strictures in PSARP patients ↗
▶ Ep 197 · 1:20
clinical HMA is performed by making incisions at 12, 3, 6, and 9 o'clock positions creating a rhomboid shape that opens the strictured area ↗
▶ Ep 197 · 1:30
clinical HMA does not require flaps or mobilization of the rectum ↗
▶ Ep 197 · 1:34
clinical HMA is safe, effective, and minimally invasive ↗
▶ Ep 197 · 1:38
clinical HMA can be done outpatient as an alternative to long-term dilations after PSARP ↗
▶ Ep 197 · 2:09
clinical Anal dilations can cause stress for families ↗
▶ Ep 197 · 2:09
clinical There isn't strong evidence to support mandatory anal dilation after PSARP ↗
▶ Ep 197 · 2:17
opinion Age of patient and access to returning for outpatient procedure are considerations when deciding on dilations ↗

Update Course Rewind 2025: Hirschsprung’s Pull-Through: Why Family Training May Save Lives

▶ Ep 198 · 0:59
epidemiological The median age of the neonatal group was 11 days at time of surgery ↗
▶ Ep 198 · 1:02
epidemiological The median age of the delayed group was 98 days at time of surgery ↗
▶ Ep 198 · 1:06
epidemiological The study found no difference in preoperative and postoperative enterocolitis between neonatal and delayed pull-through groups ↗
▶ Ep 198 · 1:06
epidemiological The study found no difference in fecal incontinence at follow-up between neonatal and delayed pull-through groups ↗
▶ Ep 198 · 1:42
epidemiological Studies show no difference in complications between neonatal and delayed pull-through procedures for Hirschsprung patients ↗
▶ Ep 198 · 1:50
opinion Decisions on timing should factor in the family's ability to perform irrigations ↗

Update Course Rewind 2025: Botox for Hirschsprung’s: Where, When, and Why

▶ Ep 199 · 0:45
epidemiological A 2022 multi-center study found that 24% of patients undergoing pull-through procedure also received Botox ↗
▶ Ep 199 · 1:09
clinical Patients that received Botox had a higher chance of diaper rash ↗
▶ Ep 199 · 1:37
clinical Injecting Botox during pull-through procedure for Hirschsprung's disease has been shown to reduce enterocolitis risk ↗
▶ Ep 199 · 1:41
epidemiological Dosing and guidance for Botox injection varies widely ↗

Update Course Rewind 2025: Hirschsprung + ARM: Rare but Real

▶ Ep 200 · 0:34
quote The correct answer is less than 2%. ↗
▶ Ep 200 · 0:34
epidemiological The rate of Hirschsprung disease and anorectal malformation occurring together is less than 2% ↗
▶ Ep 200 · 0:37
quote It's rare, but something to keep in mind for patients with trisomy 21. ↗
▶ Ep 200 · 0:37
clinical The co-occurrence of Hirschsprung disease and ARM is something to keep in mind for patients with trisomy 21 ↗
▶ Ep 200 · 0:58
clinical Hypo or absent ganglion cells were found in the remaining specimens (9%) ↗
▶ Ep 200 · 0:58
clinical Ganglion cells were found in 91% of rectal fistula specimens ↗
▶ Ep 200 · 1:05
clinical Absent ganglion cells in fistula tissue does not necessarily mean the patient has Hirschsprung disease ↗
▶ Ep 200 · 1:05
quote But absent cells in fistula tissue doesn't necessarily mean it's Hirschsprung's disease. ↗
▶ Ep 200 · 1:11
epidemiological Three patients (4% of the cohort) had both Hirschsprung disease and an anorectal malformation ↗
▶ Ep 200 · 1:15
epidemiological Two of the three patients with both conditions also had trisomy 21 ↗
▶ Ep 200 · 1:31
guideline Complex anorectal malformation patients with chromosomal anomalies who do not respond to laxatives or enemas should be worked up for Hirschsprung disease ↗

Update Course Rewind 2025: Hirschsprung + ARM: Rare but Real

▶ Ep 201 · 0:34
quote The correct answer is less than 2%. ↗
▶ Ep 201 · 0:34
epidemiological The rate of Hirschsprung disease and anorectal malformation occurring together is less than 2% ↗
▶ Ep 201 · 0:37
quote It's rare, but something to keep in mind for patients with trisomy 21. ↗
▶ Ep 201 · 0:37
clinical The co-occurrence of Hirschsprung disease and ARM is something to keep in mind for patients with trisomy 21 ↗
▶ Ep 201 · 0:58
clinical Hypo or absent ganglion cells were found in the remaining rectal fistula specimens ↗
▶ Ep 201 · 0:58
clinical Ganglion cells were found in 91% of rectal fistula specimens ↗
▶ Ep 201 · 1:05
clinical Absent ganglion cells in fistula tissue does not necessarily mean the patient has Hirschsprung disease ↗
▶ Ep 201 · 1:05
quote But absent cells in fistula tissue doesn't necessarily mean it's Hirschsprung's disease. ↗
▶ Ep 201 · 1:11
epidemiological Three patients (4% of the study cohort) had both Hirschsprung disease and anorectal malformation ↗
▶ Ep 201 · 1:15
epidemiological Two of the three patients with both conditions had trisomy 21 ↗
▶ Ep 201 · 1:31
guideline Complex anorectal malformation patients with chromosomal anomalies who do not respond to laxatives or enemas should be worked up for Hirschsprung disease ↗
Fetal Surgery 7 entries

Inside a FETO Procedure: Fetoscopic Balloon Tracheal Occlusion with Dr. Beth Rymeski

▶ Ep 29 · 0:47
clinical The goal of FETO is to allow fluid to stay in the lungs and allow the lungs to expand and grow ↗
▶ Ep 29 · 0:53
clinical FETO helps prevent pulmonary hypoplasia, which is a big factor in poor outcomes for CDH babies ↗
▶ Ep 29 · 3:08
clinical The balloon is filled with water, around 0.65 to 0.8 mL, depending on the size of the trachea ↗
▶ Ep 29 · 3:40
clinical Final confirmation requires advancing the scope one more time to verify the balloon is below the vocal cords and in the main trachea ↗

Inside a FETO Procedure: Fetoscopic Balloon Tracheal Occlusion with Dr. Beth Rymeski

▶ Ep 30 · 0:47
clinical The goal of FETO is to allow fluid to stay in the lungs and allow the lungs to expand and grow ↗
▶ Ep 30 · 0:53
clinical FETO helps prevent pulmonary hypoplasia, which is a big factor in poor outcomes for CDH babies ↗
▶ Ep 30 · 3:08
clinical The balloon is filled with water, around 0.65 to 0.8 mL, depending on the size of the trachea ↗
Inguinal Hernia 21 entries

Surgeon annual volume impacts recurrence rates of pediatric inguinal hernia repairs: A multi-institutional study

▶ Ep 22 · 0:10
epidemiological Heller et al. published a multi-institutional study in the Journal of Pediatric Surgery in 2025 ↗
▶ Ep 22 · 0:22
quote The authors found that inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence. ↗
▶ Ep 22 · 0:22
epidemiological Inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence ↗
▶ Ep 22 · 0:30
epidemiological There was no difference in recurrence rates for open repairs based on surgeon volume ↗
▶ Ep 22 · 0:35
quote However, laparoscopic repairs done by lower volume surgeons had a 3.3 fold increase in the odds of recurrence. ↗
▶ Ep 22 · 0:35
epidemiological Laparoscopic repairs done by lower volume surgeons had a 3.3 fold increase in the odds of recurrence ↗
▶ Ep 22 · 0:44
guideline The authors recommend maintaining a high volume of laparoscopic repairs, and if that's not possible, to seek help from a higher volume surgeon ↗

Laparoscopic modified percutaneous internal ring suturing - a mesh-free alternative for indirect inguinal hernia repair in adults. a pilot prospective cohort study

▶ Ep 23 · 0:00
quote High ligation hernia repair, that's for kids. ↗
▶ Ep 23 · 0:00
clinical High ligation hernia repair is traditionally a pediatric technique ↗
▶ Ep 23 · 0:03
quote Or is it? ↗
▶ Ep 23 · 0:08
clinical The study was published in the International Journal of Surgery ↗
▶ Ep 23 · 0:12
clinical The study used modified percutaneous internal ring suturing technique for laparoscopic non-mesh repair of indirect inguinal hernias in adults ↗
▶ Ep 23 · 0:23
epidemiological The study included 20 patients ↗
▶ Ep 23 · 0:25
epidemiological The majority of patients were male ↗
▶ Ep 23 · 0:26
epidemiological Median follow-up duration was 79 months ↗
▶ Ep 23 · 0:26
clinical No patients had hernia recurrence on follow-up ↗
▶ Ep 23 · 0:31
clinical Patients reported a decrease in pain postoperatively ↗
▶ Ep 23 · 0:31
clinical Patients reported improved activity postoperatively ↗
▶ Ep 23 · 0:35
opinion This is a small single-center study ↗
▶ Ep 23 · 0:35
opinion The study shows success with this technique in adults ↗
▶ Ep 23 · 0:41
quote Would you offer this to your hernia patients? ↗
Liver Tumors (Hepatoblastoma/HCC) 16 entries

Characteristics of Transfusion and Association With Oncologic Outcomes in Hepatoblastoma Resection

▶ Ep 16 · 0:00
clinical It is not uncommon for a patient with hepatoblastoma to need a transfusion during resection ↗
▶ Ep 16 · 0:00
quote It's not uncommon for a patient with hepatoblastoma to need a transfusion during resection. ↗
▶ Ep 16 · 0:13
epidemiological The study was multi-institutional and published in Pediatric Blood and Cancer in 2025 ↗
▶ Ep 16 · 0:19
epidemiological The study examined how intraoperative transfusion may affect recurrence and survival in hepatoblastoma resection patients ↗
▶ Ep 16 · 0:25
epidemiological Of those transfused, the majority received red blood cells ↗
▶ Ep 16 · 0:25
epidemiological Only 11% of transfused patients received platelets ↗
▶ Ep 16 · 0:32
quote Intraoperative blood transfusions had no effect on recurrence, however, they were associated with increased death. ↗
▶ Ep 16 · 0:32
clinical Intraoperative blood transfusions were associated with increased death ↗
▶ Ep 16 · 0:32
clinical Intraoperative blood transfusions had no effect on recurrence ↗
▶ Ep 16 · 0:39
clinical There were instances of unnecessary blood transfusions ↗
▶ Ep 16 · 0:43
clinical Patients who were transfused had higher post-op hemoglobin ↗
▶ Ep 16 · 0:43
clinical Transfused patients still required more plasma and platelets postoperatively ↗
▶ Ep 16 · 0:52
quote The authors think that blood transfusions were mostly red blood cells, and that is what contributed to the post-op coagulopathy. ↗
▶ Ep 16 · 0:52
opinion The authors think that blood transfusions were mostly red blood cells, and that is what contributed to the post-op coagulopathy ↗
▶ Ep 16 · 1:00
guideline The authors recommend a balanced transfusion approach ↗
▶ Ep 16 · 1:00
guideline The authors recommend more careful patient selection for intraoperative transfusions ↗
Neurofibromatosis 15 entries

Malignant peripheral nerve sheath tumors: a report from Children’s Oncology Group study ARST0332

▶ Ep 1 · 0:00
quote Is there a role for chemo radiation in peripheral nerve sheath tumors, or is excision all that is needed? ↗
▶ Ep 1 · 0:11
clinical The Children's Oncology Group published a prospective trial on malignant peripheral nerve sheath tumors in the Journal of the National Cancer Institute in 2025. ↗
▶ Ep 1 · 0:24
clinical Patients were assigned to four treatment groups: observation, adjuvant radiation, adjuvant chemoradiation, and neoadjuvant chemoradiation. ↗
▶ Ep 1 · 0:35
clinical Resection has a major influence on survival for patients with malignant peripheral nerve sheath tumors. ↗
▶ Ep 1 · 0:35
quote Overall results confirmed that resection has a major influence on survival for these patients. ↗
▶ Ep 1 · 0:40
epidemiological Female patients with malignant peripheral nerve sheath tumors had improved outcomes. ↗
▶ Ep 1 · 0:40
clinical Low-risk patients had improved outcomes. ↗
▶ Ep 1 · 0:40
clinical Patients without metastatic disease had improved outcomes. ↗
▶ Ep 1 · 0:46
clinical In patients receiving neoadjuvant therapy, 45% were stable. ↗
▶ Ep 1 · 0:46
clinical In patients receiving neoadjuvant therapy, 32% had progressive disease. ↗
▶ Ep 1 · 0:46
clinical In patients receiving neoadjuvant therapy, 23% showed a response. ↗
▶ Ep 1 · 0:59
clinical There was no difference in survival based on the response to neoadjuvant therapy among patients who went on to have resection. ↗
▶ Ep 1 · 0:59
quote There was no difference in survival based on the response to neoadjuvant therapy. ↗
▶ Ep 1 · 1:03
guideline Resection should be done for patients with malignant peripheral nerve sheath tumors whenever possible, even if they show a good response to chemoradiation. ↗
▶ Ep 1 · 1:03
quote Overall, this study confirms that resection should be done for these patients whenever possible, even if they show a good response to chemo radiation. ↗
Pediatric Robotic Surgery 14 entries

Update Course Rewind 2025: Robotics in Pediatric Surgery: Which indications benefit the most?

▶ Ep 7 · 0:33
opinion All pediatric surgical patients discussed are good candidates for robotic surgery ↗
▶ Ep 7 · 1:02
clinical Robotic surgery reduces postoperative pain and infection risk, leading to faster recovery ↗
▶ Ep 7 · 1:56
opinion Improved efficiency and reduced operative time reduces costs for robotics in the long run ↗
▶ Ep 7 · 2:09
clinical Robotic surgery improves depth perception compared to laparoscopic surgery ↗
▶ Ep 7 · 2:14
clinical Robotic surgery reduces surgeon fatigue compared to laparoscopic surgery ↗
▶ Ep 7 · 2:23
clinical In colorectal surgery, robotic operative time is longer than laparoscopic ↗
▶ Ep 7 · 2:23
clinical Laparoscopy has a higher conversion rate to open surgery than robotic surgery in colorectal cases ↗
▶ Ep 7 · 2:32
clinical Both robotic and laparoscopic surgery have comparable oncologic results ↗
▶ Ep 7 · 2:57
clinical It takes half the number of cases to become proficient in robotic surgery versus laparoscopy ↗
▶ Ep 7 · 3:14
clinical Robotics can be indicated for surgeries in the chest, pelvic reconstruction, abdominal tumors, and urology ↗
▶ Ep 7 · 3:24
clinical In smaller patients, measure 3 centimeters between ports ↗
▶ Ep 7 · 3:38
clinical Robotic surgery in pediatric patients is ideal in select cases including adrenal masses, polycystic kidneys, and nephrectomies ↗
▶ Ep 7 · 3:52
opinion Reported cons of robotic surgery include cost, set up time, the size of the ports, and a steep learning curve ↗
▶ Ep 7 · 4:06
clinical Operative times and conversions to open surgery are lower for robotic surgery compared to laparoscopy once proficiency is achieved ↗
Peritoneal Dialysis Access 7 entries

Surgeon annual volume impacts recurrence rates of pediatric inguinal hernia repairs: A multi-institutional study

▶ Ep 8 · 0:10
epidemiological Heller et al. published a multi-institutional study in the Journal of Pediatric Surgery in 2025 ↗
▶ Ep 8 · 0:22
epidemiological Inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence ↗
▶ Ep 8 · 0:22
quote The authors found that inguinal hernias repaired by lower volume surgeons had a 1.5 fold increase in the odds of recurrence. ↗
▶ Ep 8 · 0:30
epidemiological There was no difference in recurrence rates for open repairs based on surgeon volume ↗
▶ Ep 8 · 0:35
quote However, laparoscopic repairs done by lower volume surgeons had a 3.3 fold increase in the odds of recurrence. ↗
▶ Ep 8 · 0:35
epidemiological Laparoscopic repairs done by lower volume surgeons had a 3.3 fold increase in the odds of recurrence ↗
▶ Ep 8 · 0:44
guideline The authors recommend maintaining a high volume of laparoscopic repairs, and if that's not possible, to seek help from a higher volume surgeon ↗
Wilms Tumor 12 entries

Impact of Pulmonary Tumor Burden in Favorable Histology Wilms Tumor Outcomes: A Report From the Children's Oncology Group Study AREN053

▶ Ep 19 · 0:00
quote Your patient has a Wilms tumor with favorable histology, but workup shows that they also have lung metastases. ↗
▶ Ep 19 · 0:14
clinical Dick et al. published a report from a Children's Oncology Group study in the Journal of Clinical Oncology in 2025 ↗
▶ Ep 19 · 0:19
clinical The study examined factors in patients with favorable histology Wilms tumor and pulmonary metastases and how those factors may affect outcomes ↗
▶ Ep 19 · 0:30
clinical Factors studied included the number of metastases, the size of the metastases, and different biological markers ↗
▶ Ep 19 · 0:36
clinical There was no difference in survival based on the number of metastases ↗
▶ Ep 19 · 0:41
clinical Patients with larger nodules and rapid response to chemotherapy showed no changes in overall survival ↗
▶ Ep 19 · 0:41
clinical Patients who had a rapid response to chemotherapy with larger nodules showed worse event-free survival ↗
▶ Ep 19 · 0:49
clinical In multivariable models, neither the size nor the number of nodules had any effect on survival ↗
▶ Ep 19 · 0:55
clinical 1q gain was associated with worse overall survival ↗
▶ Ep 19 · 0:55
clinical 1q gain was associated with worse event-free survival ↗
▶ Ep 19 · 1:04
quote One cue gain is the superior prognostic factor when compared to size and number of nodules in patients with favorable histology Wilms and pulmonary metastases. ↗
▶ Ep 19 · 1:04
clinical 1q gain is the superior prognostic factor when compared to size and number of nodules in patients with favorable histology Wilms tumor and pulmonary metastases ↗