Does Delayed Diagnosis of Hirschsprung Disease Impact Post-operative and Functional Outcomes? A Multi-Center Review From the Pediatric Colorectal and Pelvic Learning Consortium

Who's speaking

• Alex Halpern — guest

Chapters

• 0:00Introduction — Alex Halpern introduces the research question and himself as a research fellow from Children's National.
• 0:12Study Design — Description of the multi-center retrospective review conducted by the Pediatric Colorectal and Pelvic Learning Consortium, including timeframe and patient population.
• 0:29Key Findings — Presentation of the study's main findings regarding associations between age at diagnosis and various postoperative outcomes.
• 0:58Conclusion and Call to Action — Summary conclusion that delayed diagnosis affects certain outcomes and invitation for viewer feedback.

Key claims

• 0:12The Pediatric Colorectal and Pelvic Learning Consortium conducted a multi-center retrospective review from 2017 to 2023 examining the relationship between delayed diagnosis of Hirschsprung disease and postoperative/functional outcomes. — Alex Halpern
• 0:23The study included 679 patients with Hirschsprung disease from 14 different sites. — Alex Halpern
• 0:29Increased age at diagnosis was associated with a greater likelihood of undergoing fecal diversion after initial pull-through procedure. — Alex Halpern
• 0:39Increased age at diagnosis was associated with an increased risk of constipation or incontinence requiring intervention postoperatively. — Alex Halpern
• 0:49No association was found between age at diagnosis and 30-day complication rate after initial pull-through. — Alex Halpern
• 0:49No association was found between age at diagnosis and need for pull-through revision. — Alex Halpern
• 0:58Delayed diagnosis of Hirschsprung disease affects certain postoperative and functional outcomes in patients. — Alex Halpern

Open questions

• Does this information about delayed diagnosis affecting certain Hirschsprung disease outcomes change clinical practice?