Outpatient management of intussusception: a systematic review and meta-analysis

Space: StayCurrentMD Author: Cristen N. Litz, Ernest K. Amankwah, Randall L. Polo, Kristen A. Sakmar, Paul D. Danielson, Nicole M. Chandler Published:

Author / Expert

Cristen N. Litz, Ernest K. Amankwah, Randall L. Polo, Kristen A. Sakmar, Paul D. Danielson, Nicole M. Chandler

Topic overview

Abstract

Background

Variability in management of intussusception after enema reduction exists. Historically, inpatient observation was recommended; however, there is a lack of evidence-based guidelines for this practice.

Methods

A systematic review and meta-analysis evaluating outcomes between inpatient (IP) and outpatient (OP) management after enema reduction was performed. The following databases were searched: PubMed, EBSCOhost CINAHL, EMBASE, Web of Science, and Cochrane Database. Data from an institutional review were included in the meta-analysis.

Results

Ten studies of patients aged 0–18 years with intussusception who underwent successful enema reduction that reported outcomes of outpatient management were included. Overall recurrence rates were 6% for IP and 8% for OP (p = 0.20). Recurrences within 24 (IP: 1% vs OP: 0%, p = 0.90) and 48 h (IP: 1% vs OP: 2%, p = 0.11) were similar. There was no significant difference in the rate of return to the emergency department (IP: 6% vs OP: 14%, p = 0.11). Both groups had a similar rate of requiring an operation (IP: 2% vs OP: 1%, p = 0.84).

Conclusions

Outpatient management of intussusception after enema reduction results in a shorter hospital stay with no difference in the rate of return to the emergency department, recurrence, need for operation, or mortality. The findings of the meta-analysis suggest that outpatient management may be safe and could reduce hospital resource utilization.

Type of study

Treatment study.

Level of evidence

III.

Keywords

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