Venous thromboembolism following inpatient pediatric surgery: Analysis of 153,220 patients

Space: StayCurrentMD Author: Brandon A. Sherrod, Samuel G. McClugage, Vincent E. Mortellaro, Inmaculada B. Aban, Brandon G. Rocque Published:

Author / Expert

Brandon A. Sherrod, Samuel G. McClugage, Vincent E. Mortellaro, Inmaculada B. Aban, Brandon G. Rocque

Topic overview

Abstract

Purpose

To evaluate venous thromboembolism (VTE) rates and risk factors following inpatient pediatric surgery.

Methods

153,220 inpatient pediatric surgical patients were selected from the 2012–2015 NSQIP-P database. Demographic and perioperative variables were documented. Primary outcome was VTE requiring treatment within 30 postoperative days. Secondary outcomes included length of stay (LOS) and 30-day mortality. Prediction models were generated using logistic regression. Mortality and time to VTE were assessed using Kaplan–Meier survival analysis.

Results

305 patients (0.20%) developed 296 venous thromboses and 12 pulmonary emboli (3 cooccurrences). Median time to VTE was 9 days. Most VTEs (81%) occurred predischarge. Subspecialties with highest VTE rates were cardiothoracic (0.72%) and general surgery (0.28%). No differences were seen for elective vs. urgent/emergent procedures (p = 0.106). All-cause mortality VTE patients was 1.2% vs. 0.2% in patients without VTE (p 

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