Histopathologic examination of resected nerves from children with anterior cutaneous nerve entrapment syndrome: Clues for pathogenesis?

Histopathological analysis of resected nerves from seven pediatric ACNES patients reveals non-specific nerve degeneration with CD68-positive macrophages, supporting compression rather than inflammation as the underlying mechanism. All specimens showed degenerative changes without significant inflammatory infiltrate, providing evidence for the compression hypothesis in pediatric anterior cutaneous nerve entrapment syndrome.