Ovarian tissue health after laparoscopic unilateral oophorectomy: A porcine model for establishing optimized fertility preservation techniques in children

This porcine study compared ovarian tissue viability after laparoscopic isolation using ultrasonic energy devices at varying distances versus cold scissors. Ultrasonic dissection—even beyond the reported 2cm thermal spread zone—significantly impaired folliculogenesis and hormone production, suggesting current laparoscopic techniques may compromise fertility preservation outcomes in prepubertal patients.