Cost-Effectiveness Analysis of the Surgical Management of Infants Less than One Year of Age with Feeding Difficulties

Space: StayCurrentMD Author: Yangyang R. Yu, Megan E. Cunningham, Annalyn S. DeMello, Eric H. Chiou, Panagiotis Kougias, David E. Wesson, Mary L. Brandt, Monica E. Lopez Published:

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Yangyang R. Yu, Megan E. Cunningham, Annalyn S. DeMello, Eric H. Chiou, Panagiotis Kougias, David E. Wesson, Mary L. Brandt, Monica E. Lopez

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Abstract

Background

We compared the cost-effectiveness of the common surgical strategies for the management of infants with feeding difficulty.

Methods

Infants with feeding difficulty undergoing gastrostomy alone (GT), GT and fundoplication, or gastrojejunostomy (GJ) tube were enrolled between 2/2017 and 2/2018. A validated GERD symptom severity questionnaire (GSQ) and visual analog scale (VAS) to assess quality of life (QOL) were administered at baseline, 1 month, and every 6 months. Data collected included demographics, resource utilization, diagnostic studies, and costs. VAS scores were converted to quality adjusted life months (QALMs), and costs per QALM were compared using a decision tree model.

Results

Fifty patients initially had a GT alone (71% laparoscopically), and one had a primary GJ. Median age was 4 months (IQR 3–8 months). Median follow-up was 11 months (IQR 5–13 months). Forty-three did well with GT alone. Six (12%) required conversion from GT to GJ tube, and one required a fundoplication. Of those with GT alone, six (14%) improved significantly so that their GT was removed after a mean of 7 ± 3 months. Overall, the median GSQ score improved from 173 at baseline to 18 after 1 year (p 

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