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Multiple, independent, common variants at RET, SEMA3 and NRG1 gut enhancers specify Hirschsprung disease risk in European ancestry subjects

AbstractPurposeHirschsprung disease (HSCR) is a developmental disorder of the enteric nervous system (ENS) characterized by congenital...

📅 Apr 23, 2021 articles
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Outcomes of Bariatric Surgery in Older Versus Younger Adolescents

Objectives: In this report, we compare weight loss, comorbidity resolution, nutritional abnormalities, and quality of life between younger and...

📅 Apr 23, 2021 articles
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Exploratory Assessment of Levosimendan in Infants With Congenital Diaphragmatic Hernia

Objectives: Infants with congenital diaphragmatic hernia frequently suffer from cardiac dysfunction and pulmonary hypertension during the...

📅 Apr 23, 2021 articles
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Promising Results for Hypospadias Repair Using Alloderm® (Regen): A Randomized Controlled Trial

AbstractIntroduction;Hypospadias is a congenital disorder of urethra in which meatus is not at its correct place and occurs in 1 of 250 live male...

📅 Apr 23, 2021 articles
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Laparoscopic totally extraperitoneal ligation for pediatric inguinal hernia: a novel surgical treatment

Background: Despite a number of studies comparing laparoscopic inguinal hernia repair (LH) and open herniorrhaphy (OH), the putative advantage of...

1 listens 📅 Apr 23, 2021 articles
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Prenatal diagnosis of intestinal nonrotation using magnetic resonance imaging: Is it possible?

Background: Malrotation of the bowel refers to any variation in the rotation and fixation of the gastrointestinal tract during the first trimester...

6 listens 📅 Apr 16, 2021 articles
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Epidemiology of Surgical Procedures, Anesthesia, and Imaging Studies by Gestational Age during the First Year of Life in Medicaid-Insured Infants

Objectives: To evaluate the rate of surgical procedures, anesthetic use, and imaging studies by prematurity status for the first year of life we...

📅 Apr 16, 2021 articles
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Association of Cryoprecipitate Use With Survival After Major Trauma in Children Receiving Massive Transfusion

Importance: Although most massive transfusion protocols incorporate cryoprecipitate in the treatment of hemorrhaging injured patients, minimal...

📅 Apr 15, 2021 articles
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Increased Incidence of Inflammatory Bowel Disease After Hirschsprung Disease: A Population-based Cohort Study

Objective: To determine the frequency with which inflammatory bowel disease (IBD) is diagnosed in persons with Hirschsprung disease in...

2 listens 📅 Apr 14, 2021 articles
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The Risk of Necrotizing Enterocolitis following the Administration of Hyperosmolar Enteral Medications to Extremely Preterm Infants

Introduction: Necrotizing enterocolitis (NEC) is a disease predominantly affecting preterm infants. The administration of hyperosmolar solutions...

📅 Apr 14, 2021 articles
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Update Course Rewind: Pilonidal Disease 2019

Did you miss our annual Update Course? Don't worry, we are summarizing our favorite sessions from years past. In this episode, Dr. Steven Lee...

31 listens 📅 Apr 14, 2021 podcasts
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Predisposition to cancer in children and adolescents

AbstractChildhood malignancies are rarely related to known environmental exposures, and it has become increasingly evident that inherited genetic...

📅 Apr 13, 2021 articles
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Enhancing recovery after minimally invasive surgery in children: A systematic review of the literature and meta-analysis

AbstractObjective: Enhanced recovery after surgery (ERAS) has been widely implemented after minimally invasive surgeries (MIS) in adults. The aim...

📅 Apr 13, 2021 articles
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Growth Failure Prevalence in Neonates with Gastroschisis : A Statewide Cohort Study

Objectives: To perform a multicenter study to assess growth failure in hospitalized infants with gastroschisis.Study design: This study included...

📅 Apr 12, 2021 articles
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A noninvasive index to predict liver cirrhosis in biliary atresia

Background: Biliary atresia is a progressive obliterative cholangiopathy affecting both extrahepatic and intrahepatic biliary trees, resulting in...

📅 Dec 29, 2020 articles
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The Colorectal Quiz Episode 10: Total Colonic Hirschsprung Disease Part 1

We've discussed Hirschsprung Disease a lot on this podcast but we've never talked about one of the most complex forms - total colonic hirschsprung...

26 listens 📅 Apr 12, 2021 podcasts
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Clinical and Esophagoenteroduodenoscopy Findings in Pediatric Patients with Severe Obesity Evaluated Prior to Bariatric Surgery

Objectives: Severe obesity in the pediatric population has lifelong consequences. Bariatric surgery has been suggested for selected adolescents...

📅 Apr 12, 2021 articles
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Epidemiology and outcomes of primary pediatric lung malignancies: Updates from the SEER database

Background: Primary pediatric lung malignancies are rare tumors. We provide an updated analysis of the epidemiology and prognosis of these tumors...

📅 Apr 12, 2021 articles
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Confirmatory radiographs have limited utility following ultrasound-guided tunneled femoral central venous catheter placements by interventional radiology

Background: Ultrasonography may reliably visualize both appropriately positioned and malpositioned femoral-approach catheter tips. Radiography may...

📅 Apr 12, 2021 articles
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CONSERVATIVE MANAGEMENT OF ANTERIOR LOCATED ANUS: A MEDIUM-LONG TERM FOLLOW UP

ABSTRACTBackground/PurposeThe anterior anus (AA) is a condition, almost exclusively present in females, in which the anus is located abnormally...

1 listens 📅 Apr 12, 2021 articles
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Papillary Thyroid Carcinoma in Children: Clinicopathological Profile and Outcomes of Management

Background: We aim to analyze the clinicopathological profile and outcomes of management for children with papillary thyroid carcinoma...

📅 Apr 12, 2021 articles
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Granulocyte-Colony Stimulating Factor GCSF Mobilizes Hematopoietic Stem Cells in Kasai Patients with Biliary Atresia in a Phase 1 Study and Improves Short Term Outcome

AbstractAimsIn RCT of adults with decompensated cirrhosis, GCSF mobilizes hematopoietic stem cells HSC and improves short-term outcome. An FDA-IND...

1 listens 📅 Apr 12, 2021 articles
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Update on Pediatric Testicular Germ Cell Tumors

AbstractBackgroundTesticular germ cell tumors are uncommon tumors that are encountered by pediatric surgeons and urologists and require a...

1 listens 📅 Apr 12, 2021 articles
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Impact of serum autotaxin level correlating with histological findings in biliary atresia

AbstractPurposePortoenterostomy is the standard treatment for biliary atresia (BA) that reduces jaundice in two thirds of cases. However,...

📅 Apr 12, 2021 articles
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Engineering Alginate Microparticles for Optimized Accumulation in Fetal Rat Myelomeningocele

AbstractIntroductionIntraamniotic microparticle injection is a novel technique for the treatment of MMC in which microparticles are delivered...

📅 Apr 12, 2021 articles
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Secondary Overtriage in a Pediatric Level One Trauma Center

AbstractBackgroundPrevious studies have explored under- and overtriage, and the means by which to optimize these rates. Few have examined...

📅 Apr 12, 2021 articles
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A Higher Incidence of Isolated Biliary Atresia in Rural Areas: Results From an Epidemiological Study in The Netherlands

Objectives: Environmental factors may be involved in the pathogenesis of biliary atresia (BA). This epidemiological study aimed to analyze the...

1 listens 📅 Apr 12, 2021 articles
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Gastric Bezoar: Retrieve it, Leave it, or Disbelieve it?

Objectives: To determine the demographics, potential risk factors, endoscopic interventions and outcomes relating to gastric bezoars in pediatric...

📅 Apr 12, 2021 articles
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CLASSIFICATION OF RARE DISEASES; A COMMENT ON ‘ATLAS OF ESOPHAGEAL ATRESIA’

Esophageal atresia (EA) is the most common congenital anomaly of esophagus with different anatomical variations [1]. Congenital esophageal web...

📅 Apr 12, 2021 articles
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Thoracoscopic lobectomy through the pulmonary hilum approach for the treatment of congenital lung malformation

Background: Thoracoscopic lobectomy is widely accepted for the treatment of congenital lung malformations (CLM), owing to its advantages. However,...

1 listens 📅 Apr 12, 2021 articles
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Inguinal Hernias: Diagnosis and Management

Inguinal hernia repair is the second most common surgery performed by pediatric surgeons. Here, we discuss the basics of diagnosis and management...

135 listens 📅 Apr 07, 2021 podcasts
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Modified percutaneous internal ring suturing with peritoneal injury in children: matched comparison to open hernia repair

Background: The aim of this study was to elucidate the outcomes of percutaneous internal ring suture (PIRS) technique for inguinal hernia repair...

📅 Apr 12, 2021 articles
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Risk of Cancers in Patients with Pediatric Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis

Objectives: We performed a systematic review and meta-analysis to evaluate the risk of the development of cancers in patients with pediatric-onset...

📅 Apr 12, 2021 articles
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Social and financial barriers may contribute to a "hidden mortality" in Uganda for children with congenital anomalies

Background: The true incidence of congenital anomalies in sub-Saharan Africa is unknown. Owing to complex challenges associated with congenital...

📅 Dec 29, 2020 articles
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The Colorectal Quiz Episode 9: Motility Disorders Part 2

Motility disorder is a team sport - that's why today, we're talking to our colleagues in Pediatric Gastroenterology, Dr. Anil Drabari from...

17 listens 📅 Apr 05, 2021 podcasts
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Use of Expedited Post-Operative Protocol for Children Undergoing Appendicostomy Reduces Length of Hospitalization

AbstractBackgroundAn appendicostomy (ACE) is a surgical option for antegrade enemas in children with severe constipation and/or fecal incontinence...

📅 Apr 12, 2021 articles