Update Course Rewind: Pectus Excavatum 2021
Inside this episode
Kai, the Library's AI content creator,
listened to this episode and mapped who's speaking, the chapters,
key claims, and cases. Every item links to the exact moment in the
recording.
AI-enriched
Inside this episode
Who's speaking
- Ellen Ancisco — host
- Ellen Ancisco — host
- Sean Saint Peter — guest
- Sean Saint Peter — guest
- Victor Garcia — guest
- Steven Rothenberg — guest
- Todd Ponsky — guest
- Todd Ponsky — guest
- Bethany Slater — guest
Chapters
- 0:00Introduction and Case Presentation — Podcast hosts introduce the episode topic and Dr. Steven Lee presents a case of a 16-year-old with pectus excavatum (pectus index 5.5) and shortness of breath on exertion, raising the question of optimal perioperative pain control.
- 1:57Cryoanalgesia for Pain Management — Discussion of cryoanalgesia technique, mechanism, application (ribs 4-7, 2 minutes per rib), and outcomes showing reduction in length of stay from 4 days to 1 day and dramatic reduction in opioid use. Dr. Garcia raises concerns about lack of long-term safety data and regulatory differences between drugs and devices.
- 4:53Alternative Pain Management Strategies — Presentation of erector spinal catheters as an alternative achieving two-day length of stay with reduced opioid requirements, and multimodal pain regimens including gabapentin, methadone, clonidine, and non-pharmacologic approaches achieving under two-day stays.
- 7:22Surgical Technique Updates — Discussion of technical considerations including bar length selection (shorter bars provide more sternal pressure and stability), sternal elevator use for safety and visualization, subxiphoid incision approaches, and debate over right-to-left versus left-to-right bar passage direction.
- 10:28Summary and Closing — Hosts summarize key points on pain management options and surgical safety techniques, followed by promotional content for the podcast and upcoming course.
Key claims
- 1:07A randomized trial of 110 patients comparing epidural and PCA for pectus excavatum pain control showed epidurals did not provide superior pain relief — Sean Saint Peter
- 1:33After implementing cryoanalgesia, patients went home on post-operative day one, leading to loss of equipoise in the trial comparing it to epidural/PCA — Sean Saint Peter
- 1:57Cryoanalgesia uses cold temperatures to cause a conduction block that interrupts pain impulses to the brain — Ellen Ancisco
- 2:19Cryoanalgesia technique involves freezing underneath ribs 4 through 7 for 2 minutes per rib — Sean Saint Peter
- 2:29Cryoanalgesia should not be performed on rib 8 or below due to risk of abdominal wall paralysis — Sean Saint Peter
- 2:37With cryoanalgesia, length of stay decreased from 4 days to 1 day — Sean Saint Peter
- 2:46Cryoanalgesia dramatically reduced median morphine equivalents compared to previous pain management approaches — Sean Saint Peter
- 3:04There are no long-term studies on cryoanalgesia outcomes — Victor Garcia
- 3:24Medical devices and implants are not required to undergo clinical trials before market introduction, unlike drugs — Victor Garcia
- 4:09Erector spinal catheters are placed by the pain team with ultrasound guidance and are juxtaposed to but not in the vertebral space — Victor Garcia
- 4:19With erector spinal catheters, hospital stay is 2 days, catheters stay in for 5 days total, and are removed by family on day 3 at home — Victor Garcia
- 4:33Erector spinal catheters reduced opioid requirements both in hospital and after discharge — Victor Garcia
- 5:08Cryoanalgesia changed patient condition at discharge - not just earlier discharge but better functional status at time of discharge — Steven Rothenberg
- 6:02Multimodal pain therapy should include preoperative counseling, gabapentin pre and postoperatively, methadone, clonidine, bowel regimen medications, and anti-emetics — Todd Ponsky
- 6:19With multimodal pain regimen at Nebraska, length of stay is under 2 days and patients are off opioids by 1 week — Todd Ponsky
- 6:39Bar flips typically occur early and are due to the bar sitting in a bad position, not being wrapped tight enough, or not being secured well — Sean Saint Peter
- 6:59Bar flippage is completely a surgical technique issue — Steven Rothenberg
- 7:40Computational modeling shows shorter flat bars have more pressure on the sternum and are therefore more stable than traditional U-shaped bars — Todd Ponsky
- 8:27Sternal elevator use allows less tissue damage and better repair in deep stiff pectus cases — Steven Rothenberg
- 8:40Sternal elevator allows entry and exit at the same interspace — Victor Garcia
- 9:31Passing the bar from left chest to right chest is safer because the opposite direction points the instrument directly at the ventricle — Bethany Slater
Cases discussed
- 0:3616-year-old male with pectus excavatum presenting for chest wall reconstruction
Points of disagreement
- 3:01Adoption of cryoanalgesia for pectus excavatum pain management
- Sean Saint Peter: Strongly supports cryoanalgesia based on dramatic improvements in length of stay and opioid reduction
- Victor Garcia: Acknowledges cryoanalgesia works but concerned about lack of long-term safety data and advocates for erector spinal catheters as alternative with known safety profile
- Steven Rothenberg: Initially skeptical but became convinced after seeing patient outcomes, though accepts validity of safety concerns
- 8:08Frequency of sternal elevator use
- Victor Garcia: Uses sternal elevator in every case for safety and consistent visualization
- Steven Rothenberg: Uses sternal elevator in only 10% of cases, primarily for deep stiff pectus, as thoracoscopy provides adequate visualization in average younger patients
- 9:23Direction of bar passage (right-to-left vs left-to-right)
- Bethany Slater: Passes from left chest to right chest because opposite direction points instrument at ventricle
- Ellen Ancisco: Always done right to left and never considered left to right
- Sean Saint Peter: Believes it is surgeon preference and direction does not matter as long as substernal space is well dissected
Open questions
- What are the long-term outcomes and potential complications of cryoanalgesia, particularly regarding chronic neuropathic pain?
- Should there be a registry established to track long-term cryoanalgesia outcomes?
- What is the optimal bar length for pectus excavatum repair to balance stability and outcomes?
- Is sternal elevator use necessary in all cases or only in select anatomically challenging cases?
- Does the direction of bar passage (right-to-left vs left-to-right) impact safety outcomes when adequate visualization is achieved?
Cryoanalgesia Transforms Pectus Excavatum Recovery: A Paradigm Shift in Perioperative Pain Control
The patient case from this episode, retold from presentation to outcome with the decisions made along the way.
Written by Kai from the episode transcript and reviewed before
publishing.
For the care team · Case narrative · AI-written, human-reviewed
Cryoanalgesia Transforms Pectus Excavatum Recovery: A Paradigm Shift in Perioperative Pain Control
The Case
A 16-year-old male presented with exertional dyspnea and a pectus index of 5.5 — severe enough to warrant chest wall reconstruction 1:07. He had no comorbidities. The surgical plan was straightforward; the pain management was not.
The Decision Point
For years, pectus excavatum repair meant a predictable four-day hospital stay dominated by opioid management and the complications that follow: ileus, nausea, sedation, and the risk of persistent use. A randomized trial of 110 patients comparing epidural to patient-controlled analgesia had shown no meaningful difference — neither approach reliably shortened the stay or reduced opioid burden 1:07. The team at Children's Mercy Hospital had started a new trial comparing these standard approaches to intercostal nerve cryoablation, a technique that uses a two-minute freeze cycle per rib to interrupt pain transmission [c3, c4]. The probe is placed under ribs 4 through 7 under thoracoscopic guidance; rib 8 and below are avoided due to the risk of abdominal wall paralysis 2:29.
Then the first cryoanalgesia patient went home on postoperative day one 1:33. One of the discussants described the shift in perspective that followed [q1]. Equipoise collapsed. The trial stopped.
What They Did
The team adopted cryoanalgesia as their standard approach. The technique is simple: "You literally just count down to the 4th rib and then freeze underneath it" [q2]. Two minutes per rib, four ribs total. Length of stay dropped from four days to one 2:37. Median morphine equivalents — already low with epidural or PCA — fell to levels that were "not even really on the same planet" 2:46.
But not every center followed. At Cincinnati Children's Hospital, the response was cautious. "I agree with Sean. It works. I mean, it is great, one day" [q4], but "we don't have the long-term data" [q5]. The concern was chronic neuropathic pain — a known risk with nerve injury, and one that would not declare itself in the first postoperative week. Medical devices and implants, unlike drugs, are not required to undergo clinical trials before market introduction 3:24. The long-term safety data simply do not exist.
Cincinnati adopted erector spinae catheters instead. Placed by the pain service under ultrasound guidance, the catheters sit adjacent to — not within — the vertebral space 4:09. Patients go home on postoperative day two with the catheter in place; families remove it at home on day three, for a total of five days of regional analgesia 4:19. The approach reduced opioid requirements both in-hospital and after discharge 4:33, though not to the degree seen with cryoanalgesia.
At Rocky Mountain Children's Hospital, the conversion was slower. "I was a cryo skeptic" [q7], citing concerns about operative time and neuralgia risk. Four cases changed that assessment. "It's not just when they go home, it's how they feel when they go home, and the cryo has been unbelievable" [q8]. The functional status at discharge — not merely the timing — was different 5:08. "I feel bad that I waited so long" [q9].
The Outcome
The case presentation did not include long-term follow-up. What was discussed was the immediate postoperative course: one-day discharge, minimal opioid use, and early return to function. Whether this comes at the cost of delayed neuropathic pain remains unknown.
What the Case Changes
The transferable judgment is this: when a new technique produces results an order of magnitude better than the standard, the question is not whether to adopt it — the question is what you are willing to accept as sufficient evidence. Cryoanalgesia works. The one-day discharge is reproducible across centers. The opioid reduction is dramatic. The long-term nerve outcomes are unstudied.
For centers willing to accept device-level evidence standards, cryoanalgesia is now the benchmark. For centers requiring drug-level evidence, erector spinae catheters offer a middle path: better than epidural, not as effective as cryoablation, and with a mechanism that does not involve deliberate nerve injury. A well-constructed multimodal regimen — preoperative counseling, gabapentin, methadone, clonidine, bowel regimen, antiemetics 6:02 — can achieve discharge under two days and opioid cessation by one week 6:19, approaching cryoanalgesia outcomes without the unknown tail risk.
The other lesson is about equipoise. Once you see a patient walk out on day one, it becomes difficult to justify a four-day stay for the next one. That is not a failure of scientific rigor — it is the correct response to a large treatment effect. The question is whether the effect you are seeing is the whole story.
Takeaways from this story
- Cryoanalgesia reduced pectus excavatum hospital stay from 4 days to 1 day and dramatically cut opioid use, but long-term nerve outcomes remain unstudied.
- Erector spinae catheters offer a middle path: 2-day stays, reduced opioids, and a mechanism that avoids deliberate nerve injury.
- Multimodal regimens with gabapentin, methadone, and clonidine can achieve under 2-day stays and 1-week opioid cessation without regional techniques.
- Medical devices bypass the clinical trial requirements applied to drugs, leaving safety questions unanswered at time of adoption.
Topic overview
A podcast summary of a 2021 pediatric surgery update course session focused on pectus excavatum repair, specifically perioperative pain control and surgical technique updates. The discussion centers on cryoanalgesia as a pain management strategy that reduces length of stay to one day and dramatically decreases opioid use compared to epidural or PCA, though long-term safety data remain absent. Alternative approaches include erector spinal catheters (two-day length of stay) and multimodal regimens. Technical considerations include sternal elevator use, bar length selection favoring shorter bars for stability, and safe introducer passage techniques.
Key takeaways
- Cryoanalgesia (ribs 4-7, 2min each) cuts LOS from 4 to 1 day and dramatically reduces opioid use vs epidural/PCA. (2:19)
- No long-term safety data exist for cryoanalgesia; medical devices bypass clinical trial requirements unlike drugs. (3:04)
- Erector spinae catheters (US-guided, 5-day course) achieve 2-day LOS and reduce opioid needs in-hospital and post-discharge. (4:09)
- Shorter flat bars provide greater sternal pressure and stability than U-shaped bars per computational modeling. (7:40)
- Pass introducer left-to-right chest to avoid directing instrument at ventricle; bar flips are purely technique-related. (6:59)
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