The main reasons for operating on asymptomatic CPAMs are: risk of malignancy both at resection and from malignant transformation later, risk of infection that will make surgery more difficult, and better compensatory lung growth if operating sooner in life.
The main reasons for operating on asymptomatic CPAMs are: risk of malignancy both at resection and from malignant transformation later, risk of infection that will make surgery more difficult, and better compensatory lung growth if operating sooner in life.
host_summaryThe Stocker classification for CPAMs ranges from type 0 to type 4, moving from proximal to distal in the bronchial tree, with type 1 (distal bronchi/proximal bronchioles) being most common at 60-70% of cases.↗
▶Ep 25 · 5:12
clinicalThe Stocker classification for CPAMs ranges from type 0 to type 4, moving from proximal to distal in the bronchial tree, with type 1 (distal bronchi/proximal bronchioles) being most common at 60-70% of cases.↗
▶Ep 25 · 6:57
clinicalCPAMs typically grow during the first 20-25 weeks of gestation and plateau around week 28.↗
▶Ep 25 · 6:57
host_summaryCPAMs typically grow during the first 20-25 weeks of gestation and plateau around week 28.↗
▶Ep 25 · 8:02
clinicalThe presence of hydrops is the strongest prognostic indicator of mortality in fetuses with CPAMs.↗
▶Ep 25 · 8:02
host_summaryThe presence of hydrops is the strongest prognostic indicator of mortality in fetuses with CPAMs.↗
▶Ep 25 · 8:02
quoteThe presence of hydrops is the strongest prognostic indicator of mortality in these patients.↗
▶Ep 25 · 8:02
quoteThe presence of hydrops is the strongest prognostic indicator of mortality in these patients.↗
▶Ep 25 · 8:41
clinicalThe CPAM volume ratio (CVR) is calculated as the CPAM's length times width times height times 0.52 divided by the head circumference.↗
▶Ep 25 · 8:41
host_summaryThe CPAM volume ratio (CVR) is calculated as the CPAM's length times width times height times 0.52 divided by the head circumference.↗
▶Ep 25 · 9:14
host_summaryIn patients with CVR over 1.6, it is estimated that 75% develop hydrops.↗
▶Ep 25 · 9:14
epidemiologicalIn patients with CVR over 1.6, it is estimated that 75% develop hydrops.↗
▶Ep 25 · 10:14
clinicalCPAMs are differentiated as microcystic (less than 5 millimeters) or macrocystic (larger than 5 millimeters).↗
▶Ep 25 · 10:14
host_summaryCPAMs are differentiated as microcystic (less than 5 millimeters) or macrocystic (larger than 5 millimeters).↗
▶Ep 25 · 22:25
host_summaryCPAMs are not well-visualized on chest X-rays and can regress or get smaller over time.↗
▶Ep 25 · 22:25
clinicalCPAMs are not well-visualized on chest X-rays and can regress or get smaller over time.↗
▶Ep 25 · 24:40
clinicalIn the United States, most surgeons resect CPAMs even if asymptomatic, while in Europe and Canada, surgeons sometimes choose to monitor asymptomatic lesions and avoid surgery.↗
▶Ep 25 · 24:40
host_summaryIn the United States, most surgeons resect CPAMs even if asymptomatic, while in Europe and Canada, surgeons sometimes choose to monitor asymptomatic lesions and avoid surgery.↗
▶Ep 25 · 25:29
opinionThe main reasons for operating on asymptomatic CPAMs are: risk of malignancy both at resection and from malignant transformation later, risk of infection that will make surgery more difficult, and better compensatory lung growth if operating sooner in life.↗
▶Ep 25 · 25:29
host_summaryThe main reasons for operating on asymptomatic CPAMs are: risk of malignancy both at resection and from malignant transformation later, risk of infection that will make surgery more difficult, and better compensatory lung growth if operating sooner in life.↗
▶Ep 25 · 26:03
host_summaryThoracoscopic lobectomy risks include bleeding, prolonged post-op mechanical ventilation, infections, air leak, pneumothorax, nerve injury, and mortality.↗
▶Ep 25 · 26:03
clinicalThoracoscopic lobectomy risks include bleeding, prolonged post-op mechanical ventilation, infections, air leak, pneumothorax, nerve injury, and mortality.↗
▶Ep 25 · 27:47
host_summaryThe particular malignancy associated with CPAM is pleuropulmonary blastoma (PPB), with risk that the lesion at birth already has malignancy and risk of malignant transformation over a person's life.↗
▶Ep 25 · 27:47
clinicalThe particular malignancy associated with CPAM is pleuropulmonary blastoma (PPB), with risk that the lesion at birth already has malignancy and risk of malignant transformation over a person's life.↗
▶Ep 25 · 30:17
host_summaryA recent study published in April 2021 found that no prenatally diagnosed lesions had malignancy, but 10% of patients diagnosed postnatally had malignancy in their resected mass.↗
▶Ep 25 · 30:17
epidemiologicalA recent study published in April 2021 found that no prenatally diagnosed lesions had malignancy, but 10% of patients diagnosed postnatally had malignancy in their resected mass.↗
▶Ep 25 · 52:39
host_summaryThe incidence of CPAMs is estimated to be about 1 in every 8,000 to 35,000 births.↗
▶Ep 25 · 52:39
epidemiologicalThe incidence of CPAMs is estimated to be about 1 in every 8,000 to 35,000 births.↗
▶Ep 25 · 52:53
epidemiological60% of prenatally diagnosed lung lesions are CPAMs, making them the most common prenatal lung lesion.↗
▶Ep 25 · 52:53
host_summary60% of prenatally diagnosed lung lesions are CPAMs, making them the most common prenatal lung lesion.↗
host_summaryThe Stocker classification for CPAMs ranges from type 0 to type 4, moving from proximal to distal in the bronchial tree, with type 1 (distal bronchi/proximal bronchioles) being most common at 60-70% of cases.↗
▶Ep 19 · 6:57
host_summaryCPAMs typically grow during the first 20-25 weeks of gestation and plateau around week 28.↗
▶Ep 19 · 8:02
host_summaryThe presence of hydrops is the strongest prognostic indicator of mortality in fetuses with CPAMs.↗
▶Ep 19 · 8:02
quoteThe presence of hydrops is the strongest prognostic indicator of mortality in these patients.↗
▶Ep 19 · 8:41
host_summaryThe CPAM volume ratio (CVR) is calculated as the CPAM's length times width times height times 0.52 divided by the head circumference.↗
▶Ep 19 · 9:14
host_summaryIn patients with CVR over 1.6, it is estimated that 75% develop hydrops.↗
▶Ep 19 · 10:14
host_summaryCPAMs are differentiated as microcystic (less than 5 millimeters) or macrocystic (larger than 5 millimeters).↗
▶Ep 19 · 22:25
host_summaryCPAMs are not well-visualized on chest X-rays and can regress or get smaller over time.↗
▶Ep 19 · 24:40
host_summaryIn the United States, most surgeons resect CPAMs even if asymptomatic, while in Europe and Canada, surgeons sometimes choose to monitor asymptomatic lesions and avoid surgery.↗
▶Ep 19 · 25:29
host_summaryThe main reasons for operating on asymptomatic CPAMs are: risk of malignancy both at resection and from malignant transformation later, risk of infection that will make surgery more difficult, and better compensatory lung growth if operating sooner in life.↗
▶Ep 19 · 26:03
host_summaryThoracoscopic lobectomy risks include bleeding, prolonged post-op mechanical ventilation, infections, air leak, pneumothorax, nerve injury, and mortality.↗
▶Ep 19 · 27:47
host_summaryThe particular malignancy associated with CPAM is pleuropulmonary blastoma (PPB), with risk that the lesion at birth already has malignancy and risk of malignant transformation over a person's life.↗
▶Ep 19 · 30:17
host_summaryA recent study published in April 2021 found that no prenatally diagnosed lesions had malignancy, but 10% of patients diagnosed postnatally had malignancy in their resected mass.↗
▶Ep 19 · 52:39
host_summaryThe incidence of CPAMs is estimated to be about 1 in every 8,000 to 35,000 births.↗
▶Ep 19 · 52:53
host_summary60% of prenatally diagnosed lung lesions are CPAMs, making them the most common prenatal lung lesion.↗
clinicalThe Stocker classification for CPAMs ranges from type 0 to type 4, moving from proximal to distal in the bronchial tree, with type 1 (distal bronchi/proximal bronchioles) being most common at 60-70% of cases.↗
▶Ep 17 · 6:57
clinicalCPAMs typically grow during the first 20-25 weeks of gestation and plateau around week 28.↗
▶Ep 17 · 8:02
clinicalThe presence of hydrops is the strongest prognostic indicator of mortality in fetuses with CPAMs.↗
▶Ep 17 · 8:02
quoteThe presence of hydrops is the strongest prognostic indicator of mortality in these patients.↗
▶Ep 17 · 8:41
clinicalThe CPAM volume ratio (CVR) is calculated as the CPAM's length times width times height times 0.52 divided by the head circumference.↗
▶Ep 17 · 9:14
epidemiologicalIn patients with CVR over 1.6, it is estimated that 75% develop hydrops.↗
▶Ep 17 · 10:14
clinicalCPAMs are differentiated as microcystic (less than 5 millimeters) or macrocystic (larger than 5 millimeters).↗
▶Ep 17 · 22:25
clinicalCPAMs are not well-visualized on chest X-rays and can regress or get smaller over time.↗
▶Ep 17 · 24:40
clinicalIn the United States, most surgeons resect CPAMs even if asymptomatic, while in Europe and Canada, surgeons sometimes choose to monitor asymptomatic lesions and avoid surgery.↗
▶Ep 17 · 25:29
opinionThe main reasons for operating on asymptomatic CPAMs are: risk of malignancy both at resection and from malignant transformation later, risk of infection that will make surgery more difficult, and better compensatory lung growth if operating sooner in life.↗
▶Ep 17 · 26:03
clinicalThoracoscopic lobectomy risks include bleeding, prolonged post-op mechanical ventilation, infections, air leak, pneumothorax, nerve injury, and mortality.↗
▶Ep 17 · 27:47
clinicalThe particular malignancy associated with CPAM is pleuropulmonary blastoma (PPB), with risk that the lesion at birth already has malignancy and risk of malignant transformation over a person's life.↗
▶Ep 17 · 30:17
epidemiologicalA recent study published in April 2021 found that no prenatally diagnosed lesions had malignancy, but 10% of patients diagnosed postnatally had malignancy in their resected mass.↗
▶Ep 17 · 52:39
epidemiologicalThe incidence of CPAMs is estimated to be about 1 in every 8,000 to 35,000 births.↗
▶Ep 17 · 52:53
epidemiological60% of prenatally diagnosed lung lesions are CPAMs, making them the most common prenatal lung lesion.↗