Everything that measures less than 1.6 is very, very low risk of developed eye drops. On the contrary, more than 1.6, we have high risk of eye drops and complications.
Everything that measures less than 1.6 is very, very low risk of developed eye drops. On the contrary, more than 1.6, we have high risk of eye drops and complications.
Everything that measures less than 1.6 is very, very low risk of developed eye drops. On the contrary, more than 1.6, we have high risk of eye drops and complications.
Open fetal surgery is the most similar to neonatal surgery, so we have the patient in our hands. We can operate in a fetus the same as we operate in a preemie.
Open Fetal Surgery & EXIT Procedure with Dr. Jose Peiro
▶Ep 22 · 0:33
quoteThe answer is very easy. It's just because we have prenatal diagnosis.↗
▶Ep 22 · 0:38
quoteSo in other words, we can detect things in utero very early in gestation.↗
▶Ep 22 · 0:47
quoteThe most important is the prenatal ultrasounds. The conventional ultrasounds at mid gestation around 20 weeks will be the best.↗
▶Ep 22 · 0:47
clinicalPrenatal ultrasound at mid-gestation around 20 weeks is the best tool for detecting fetal malformations, with high detection rates in developed countries.↗
▶Ep 22 · 1:27
clinicalDoppler ultrasound can assess fetal hemodynamic status by measuring flows in the umbilical artery, ductus venosus, and middle cerebral artery.↗
▶Ep 22 · 1:43
clinicalFetal MRI contributes to diagnosis definition after ultrasound, especially for findings in the brain, chest, and abdomen.↗
▶Ep 22 · 2:04
quoteSo that's the goal of fetal intervention. Just try to rescue or improve these conditions.↗
▶Ep 22 · 2:13
clinicalIn gastroschisis, earlier delivery can reduce bowel injury, resulting in less serositis and better recovery.↗
▶Ep 22 · 2:29
quoteOpen fetal surgery is the most similar to neonatal surgery, so we have the patient in our hands. We can operate in a fetus the same as we operate in a preemie.↗
▶Ep 22 · 2:37
quoteThe only problem is we need to open the uterus.↗
▶Ep 22 · 3:01
quoteFor that reason, all the fetal surgeons were trying to go away from fetal surgery, trying to look for minimally invasive surgery.↗
▶Ep 22 · 3:12
quoteOpen fetal surgery still is used for large, solid masses in the chest, for sacrococcial teratomass, and also for spina bifida.↗
▶Ep 22 · 3:12
clinicalOpen fetal surgery is still used for large solid chest masses, sacrococcygeal teratomas, and spina bifida.↗
▶Ep 22 · 3:30
clinicalSolid CPAM lesions grow rapidly and can cause mediastinal shift, compression of the contralateral lung and heart, leading to hydrops fetalis.↗
▶Ep 22 · 3:49
clinicalHydrops fetalis (ascites, pleural effusion, scalp edema, anasarca) is very close to fetal demise and is the usual outcome if untreated.↗
▶Ep 22 · 3:57
quoteSo hydros fetalis is very close to be complete a fetal demise. That is the usual outcome of these babies if we don't do nothing.↗
▶Ep 22 · 4:25
quoteEverything that measures less than 1.6 is very, very low risk of developed eye drops. On the contrary, more than 1.6, we have high risk of eye drops and complications.↗
▶Ep 22 · 4:25
clinicalCVR less than 1.6 indicates very low risk of hydrops; CVR greater than 1.6 indicates high risk of hydrops and complications.↗
▶Ep 22 · 4:53
quoteIt's a good rescue in more than half of these babies. So, the other half or 40%, probably don't respond very well.↗
▶Ep 22 · 4:53
epidemiologicalSteroids rescue more than half of CPAM cases; the remaining 40% do not respond well.↗
▶Ep 22 · 5:01
clinicalBefore 30 weeks, cystic CPAM can be treated with a shunt; solid CPAM requires open fetal surgery and lobectomy.↗
▶Ep 22 · 5:22
clinicalSolid sacrococcygeal teratomas are more dangerous than cystic ones due to rapid growth and vascularization visible on Doppler.↗
▶Ep 22 · 5:32
clinicalThe Altman classification used postnatally can also be applied to prenatal MRI to determine teratoma type and need for intervention.↗
▶Ep 22 · 5:51
guidelineOpen fetal surgery is the gold standard for spina bifida, though other innovations are in development.↗
▶Ep 22 · 6:04
clinicalSpina bifida originates at approximately 4 weeks of embryonic time when the neural tube fails to close.↗
▶Ep 22 · 6:16
clinicalIn spina bifida, the exposed spinal cord is damaged by contact with amniotic fluid rich in meconium and enzymes (the 'second hit'), progressively destroying neural tissue and nerves.↗
▶Ep 22 · 7:28
clinicalHydrocephalus in spina bifida requires ventriculoperitoneal shunting and causes migration disorders and heterotopia.↗
▶Ep 22 · 7:51
clinicalThe rationale for fetal spina bifida repair is to prevent amniotic fluid from touching the nerves and to stop CSF leak.↗
▶Ep 22 · 8:34
clinicalIn fetoscopic spina bifida repair, a collagen patch is introduced through the cannula for duroplasty, maintained with one stitch, followed by primary skin closure or patch.↗
▶Ep 22 · 8:58
clinicalThe EXIT procedure is performed at delivery for conditions that can cause neonatal asphyxia or difficult intubation, such as neck masses compressing the trachea, congenital airway obstruction, or severe micrognathia.↗
▶Ep 22 · 9:25
clinicalDuring EXIT, placental oxygenation can be maintained for 1 to 3 hours, providing a controlled situation without need to rush airway securement.↗
▶Ep 22 · 9:48
clinicalDuring EXIT for neck teratomas, if intubation is not possible with rigid instruments or laryngoscopy, partial resection of the teratoma can be performed to identify the trachea and then intubate.↗
▶Ep 22 · 10:10
clinicalOnce intubation is achieved during EXIT, the cord is clamped and complete teratoma resection is performed in an adjacent operating room.↗
Open Fetal Surgery & EXIT Procedure with Dr. Jose Peiro
▶Ep 23 · 0:33
quoteThe answer is very easy. It's just because we have prenatal diagnosis.↗
▶Ep 23 · 0:33
quoteThe answer is very easy. It's just because we have prenatal diagnosis.↗
▶Ep 23 · 0:38
quoteSo in other words, we can detect things in utero very early in gestation.↗
▶Ep 23 · 0:38
quoteSo in other words, we can detect things in utero very early in gestation.↗
▶Ep 23 · 0:47
clinicalPrenatal ultrasound at mid-gestation around 20 weeks is the best tool for detecting fetal malformations, with high detection rates in developed countries.↗
▶Ep 23 · 0:47
quoteThe most important is the prenatal ultrasounds. The conventional ultrasounds at mid gestation around 20 weeks will be the best.↗
▶Ep 23 · 0:47
clinicalPrenatal ultrasound at mid-gestation around 20 weeks is the best tool for detecting fetal malformations, with high detection rates in developed countries.↗
▶Ep 23 · 0:47
quoteThe most important is the prenatal ultrasounds. The conventional ultrasounds at mid gestation around 20 weeks will be the best.↗
▶Ep 23 · 1:27
clinicalDoppler ultrasound can assess fetal hemodynamic status by measuring flows in the umbilical artery, ductus venosus, and middle cerebral artery.↗
▶Ep 23 · 1:27
clinicalDoppler ultrasound can assess fetal hemodynamic status by measuring flows in the umbilical artery, ductus venosus, and middle cerebral artery.↗
▶Ep 23 · 1:43
clinicalFetal MRI contributes to diagnosis definition after ultrasound, especially for findings in the brain, chest, and abdomen.↗
▶Ep 23 · 1:43
clinicalFetal MRI contributes to diagnosis definition after ultrasound, especially for findings in the brain, chest, and abdomen.↗
▶Ep 23 · 2:04
quoteSo that's the goal of fetal intervention. Just try to rescue or improve these conditions.↗
▶Ep 23 · 2:04
quoteSo that's the goal of fetal intervention. Just try to rescue or improve these conditions.↗
▶Ep 23 · 2:13
clinicalIn gastroschisis, earlier delivery can reduce bowel injury, resulting in less serositis and better recovery.↗
▶Ep 23 · 2:13
clinicalIn gastroschisis, earlier delivery can reduce bowel injury, resulting in less serositis and better recovery.↗
▶Ep 23 · 2:29
quoteOpen fetal surgery is the most similar to neonatal surgery, so we have the patient in our hands. We can operate in a fetus the same as we operate in a preemie.↗
▶Ep 23 · 2:29
quoteOpen fetal surgery is the most similar to neonatal surgery, so we have the patient in our hands. We can operate in a fetus the same as we operate in a preemie.↗
▶Ep 23 · 2:37
quoteThe only problem is we need to open the uterus.↗
▶Ep 23 · 2:37
quoteThe only problem is we need to open the uterus.↗
▶Ep 23 · 3:01
quoteFor that reason, all the fetal surgeons were trying to go away from fetal surgery, trying to look for minimally invasive surgery.↗
▶Ep 23 · 3:01
quoteFor that reason, all the fetal surgeons were trying to go away from fetal surgery, trying to look for minimally invasive surgery.↗
▶Ep 23 · 3:12
quoteOpen fetal surgery still is used for large, solid masses in the chest, for sacrococcial teratomass, and also for spina bifida.↗
▶Ep 23 · 3:12
clinicalOpen fetal surgery is still used for large solid chest masses, sacrococcygeal teratomas, and spina bifida.↗
▶Ep 23 · 3:12
clinicalOpen fetal surgery is still used for large solid chest masses, sacrococcygeal teratomas, and spina bifida.↗
▶Ep 23 · 3:12
quoteOpen fetal surgery still is used for large, solid masses in the chest, for sacrococcial teratomass, and also for spina bifida.↗
▶Ep 23 · 3:30
clinicalSolid CPAM lesions grow rapidly and can cause mediastinal shift, compression of the contralateral lung and heart, leading to hydrops fetalis.↗
▶Ep 23 · 3:30
clinicalSolid CPAM lesions grow rapidly and can cause mediastinal shift, compression of the contralateral lung and heart, leading to hydrops fetalis.↗
▶Ep 23 · 3:49
clinicalHydrops fetalis (ascites, pleural effusion, scalp edema, anasarca) is very close to fetal demise and is the usual outcome if untreated.↗
▶Ep 23 · 3:49
clinicalHydrops fetalis (ascites, pleural effusion, scalp edema, anasarca) is very close to fetal demise and is the usual outcome if untreated.↗
▶Ep 23 · 3:57
quoteSo hydros fetalis is very close to be complete a fetal demise. That is the usual outcome of these babies if we don't do nothing.↗
▶Ep 23 · 3:57
quoteSo hydros fetalis is very close to be complete a fetal demise. That is the usual outcome of these babies if we don't do nothing.↗
▶Ep 23 · 4:25
clinicalCVR less than 1.6 indicates very low risk of hydrops; CVR greater than 1.6 indicates high risk of hydrops and complications.↗
▶Ep 23 · 4:25
quoteEverything that measures less than 1.6 is very, very low risk of developed eye drops. On the contrary, more than 1.6, we have high risk of eye drops and complications.↗
▶Ep 23 · 4:25
clinicalCVR less than 1.6 indicates very low risk of hydrops; CVR greater than 1.6 indicates high risk of hydrops and complications.↗
▶Ep 23 · 4:25
quoteEverything that measures less than 1.6 is very, very low risk of developed eye drops. On the contrary, more than 1.6, we have high risk of eye drops and complications.↗
▶Ep 23 · 4:53
quoteIt's a good rescue in more than half of these babies. So, the other half or 40%, probably don't respond very well.↗
▶Ep 23 · 4:53
epidemiologicalSteroids rescue more than half of CPAM cases; the remaining 40% do not respond well.↗
▶Ep 23 · 4:53
epidemiologicalSteroids rescue more than half of CPAM cases; the remaining 40% do not respond well.↗
▶Ep 23 · 4:53
quoteIt's a good rescue in more than half of these babies. So, the other half or 40%, probably don't respond very well.↗
▶Ep 23 · 5:01
clinicalBefore 30 weeks, cystic CPAM can be treated with a shunt; solid CPAM requires open fetal surgery and lobectomy.↗
▶Ep 23 · 5:01
clinicalBefore 30 weeks, cystic CPAM can be treated with a shunt; solid CPAM requires open fetal surgery and lobectomy.↗
▶Ep 23 · 5:22
clinicalSolid sacrococcygeal teratomas are more dangerous than cystic ones due to rapid growth and vascularization visible on Doppler.↗
▶Ep 23 · 5:22
clinicalSolid sacrococcygeal teratomas are more dangerous than cystic ones due to rapid growth and vascularization visible on Doppler.↗
▶Ep 23 · 5:32
clinicalThe Altman classification used postnatally can also be applied to prenatal MRI to determine teratoma type and need for intervention.↗
▶Ep 23 · 5:32
clinicalThe Altman classification used postnatally can also be applied to prenatal MRI to determine teratoma type and need for intervention.↗
▶Ep 23 · 5:51
guidelineOpen fetal surgery is the gold standard for spina bifida, though other innovations are in development.↗
▶Ep 23 · 5:51
guidelineOpen fetal surgery is the gold standard for spina bifida, though other innovations are in development.↗
▶Ep 23 · 6:04
clinicalSpina bifida originates at approximately 4 weeks of embryonic time when the neural tube fails to close.↗
▶Ep 23 · 6:04
clinicalSpina bifida originates at approximately 4 weeks of embryonic time when the neural tube fails to close.↗
▶Ep 23 · 6:16
clinicalIn spina bifida, the exposed spinal cord is damaged by contact with amniotic fluid rich in meconium and enzymes (the 'second hit'), progressively destroying neural tissue and nerves.↗
▶Ep 23 · 6:16
clinicalIn spina bifida, the exposed spinal cord is damaged by contact with amniotic fluid rich in meconium and enzymes (the 'second hit'), progressively destroying neural tissue and nerves.↗
▶Ep 23 · 7:28
clinicalHydrocephalus in spina bifida requires ventriculoperitoneal shunting and causes migration disorders and heterotopia.↗
▶Ep 23 · 7:28
clinicalHydrocephalus in spina bifida requires ventriculoperitoneal shunting and causes migration disorders and heterotopia.↗
▶Ep 23 · 7:51
clinicalThe rationale for fetal spina bifida repair is to prevent amniotic fluid from touching the nerves and to stop CSF leak.↗
▶Ep 23 · 7:51
clinicalThe rationale for fetal spina bifida repair is to prevent amniotic fluid from touching the nerves and to stop CSF leak.↗
▶Ep 23 · 8:34
clinicalIn fetoscopic spina bifida repair, a collagen patch is introduced through the cannula for duroplasty, maintained with one stitch, followed by primary skin closure or patch.↗
▶Ep 23 · 8:34
clinicalIn fetoscopic spina bifida repair, a collagen patch is introduced through the cannula for duroplasty, maintained with one stitch, followed by primary skin closure or patch.↗
▶Ep 23 · 8:58
clinicalThe EXIT procedure is performed at delivery for conditions that can cause neonatal asphyxia or difficult intubation, such as neck masses compressing the trachea, congenital airway obstruction, or severe micrognathia.↗
▶Ep 23 · 8:58
clinicalThe EXIT procedure is performed at delivery for conditions that can cause neonatal asphyxia or difficult intubation, such as neck masses compressing the trachea, congenital airway obstruction, or severe micrognathia.↗
▶Ep 23 · 9:25
clinicalDuring EXIT, placental oxygenation can be maintained for 1 to 3 hours, providing a controlled situation without need to rush airway securement.↗
▶Ep 23 · 9:25
clinicalDuring EXIT, placental oxygenation can be maintained for 1 to 3 hours, providing a controlled situation without need to rush airway securement.↗
▶Ep 23 · 9:48
clinicalDuring EXIT for neck teratomas, if intubation is not possible with rigid instruments or laryngoscopy, partial resection of the teratoma can be performed to identify the trachea and then intubate.↗
▶Ep 23 · 9:48
clinicalDuring EXIT for neck teratomas, if intubation is not possible with rigid instruments or laryngoscopy, partial resection of the teratoma can be performed to identify the trachea and then intubate.↗
▶Ep 23 · 10:10
clinicalOnce intubation is achieved during EXIT, the cord is clamped and complete teratoma resection is performed in an adjacent operating room.↗
▶Ep 23 · 10:10
clinicalOnce intubation is achieved during EXIT, the cord is clamped and complete teratoma resection is performed in an adjacent operating room.↗