Dr. Alexander Chiu · A Sinonasal Inverted Papilloma of Mixed Histology: Implications for Management of All Sinonasal Papillomas
Article1 min read·Published Jun 2026

A Sinonasal Inverted Papilloma of Mixed Histology: Implications for Management of All Sinonasal Papillomas

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Article · Jun 2026 · 1 min read

In brief

In brief

This case report describes a unique sinonasal papilloma exhibiting all three histologic subtypes (inverted, cylindrical, and fungiform) within a single specimen—the first documented case of its kind. The finding challenges traditional classification-based management approaches and suggests sinonasal papillomas may represent a spectrum rather than distinct entities.

Written by the GCMD Library team from the article.

Alexander Chiu

Sinonasal papillomas are classically categorized by their histology. Inverted, cylindrical, and fungiform are the three subtypes used to describe these lesions, and their medical and surgical management is often based on the specific subtype. We describe a case of a sinonasal papilloma with all three subtypes represented within the same surgical specimen. To our knowledge, this represents the first such case in the literature and has implications for the management of all sinonasal papillomas.

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