Vessel adherent growth represents a major challenge in the surgical resection of neuroblastoma and is associated with adverse outcome

Study of 100 neuroblastoma patients identifies unexpected vessel infiltration (UVIN) in 34% of cases, significantly correlating with incomplete resection, MYCN amplification, and poor outcomes. UVIN represents a major intraoperative challenge not visible on pre-operative imaging and is associated with higher complication rates and need for neoadjuvant therapy.