StayCurrentMD · Quick Literature Updates Episode 8
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Video·Published Jun 2023Older

Quick Literature Updates Episode 8

hosted by Dr. Em Tombash · StayCurrentMD
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What the experts said0 expert statements · 15 host summaries
The Pediatric Surgical Oncology Research Collaborative study reviewed 15 hospitals to examine how different institutions localize small pulmonary nodules in children.
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Different institutions use wires, methylene blue dye, indocyanine green, micro coils, and technetium 99 in different combinations for pulmonary nodule localization.
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There was no significant difference in the success of localization between all of the different pulmonary nodule localization techniques.
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The only significant differences in pulmonary nodule localization were in which institution performed each technique, and in IR, OR, and anesthesia times.
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In a single institution prospective study of around 40 pediatric patients who received Nuss bar repair for pectus excavatum with perioperative ERAS pain protocol, 92% of patients were discharged on post-operative day one.
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Patients receiving Nuss repair with ERAS protocol had a reduction in the total number of morphine equivalent doses received without any difference in their pain scores at the time of discharge.
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In a preclinical study of transamniotic stem cell therapy for intrauterine growth restriction, subjects were divided into four groups: untreated, saline only, MSC therapy, and MSC with primer.
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Overall survival in the intrauterine growth restriction stem cell study was 75%.
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Gross brain weight was significantly lower in IUGR subjects with no treatment or just saline, and significantly higher in those treated with MSC.
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The primed MSC group revealed significantly lowered levels of TNF alpha and interleukin beta in their brain.
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Primed MSC appears to reverse some of the central nervous system effects of intrauterine growth restriction.
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The National Trauma Data Bank analysis included over 40,000 adolescent trauma victims who were intubated for more than 24 hours and survived until discharge.
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At three days post-intubation, there was no difference in overall hospital length of stay for adolescent trauma victims receiving tracheostomy.
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In adolescent trauma victims without TBI, tracheostomy before three days decreased ICU length of stay by about 16 days compared to later tracheostomy.
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Similar trends of decreased ICU length of stay were seen for all children, regardless of TBI or non-TBI status, if they received a tracheostomy before 7 days of intubation.
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