From
Dr. Nelson G. Rosen
Pediatric pancreatitis: diagnosis, causes, and genetic insights with Dr. Juan Gurria
With Dr. Juan Gurria · hosted by Lizzy Lee, PA-C
Chapter 1 of 7
Introduction
Introduction and speaker credentials
Expert statements on this page
No expert statements were drawn from this page.
Host summaries · secondary, not cited in answers
Educational content from recorded physician discussions — not medical advice. Talk to your (or your child's) care team about your situation.
Video
Acute Pancreatitis - Pancreatic Pathologies by the Pancreas Care Center at CCHMC
CCHMC Pediatric Surgery · 4 min · Published Sep 2024
Video
Welcome and Introductions: Pancreatic Disease
Dr. Todd Ponsky · 6 min · Published Sep 2016
Video
Chronic Pancreatitis, Function Tests, & Pain Management: Pancreatic Disease
51 min · Published Sep 2016
Video
ERCP: Pancreatic Disease
CCHMC Pediatric Surgery · 9 min · Published Sep 2016
Podcast
Acute Pancreatitis
45 min · Published Jul 2017
Video
Update Course 2023 - Updates in Pancreatitis
32 min · Published Aug 2023
Podcast
Surgical management of chronic pancreatitis in children: when and how to intervene
4 min · Published Nov 2026
Podcast
Preparing for successful ECPR: team coordination and early activation strategies
2 min · Published Nov 2026
Podcast
Surgical Decision-Making in Necrotizing Enterocolitis: Imaging, Timing, and Operative Strategies
11 min · Published Nov 2026
Video
Robotics in Pediatric Surgery: Which indications benefit the most? w/ Dr. Juan Gurria
18 min · Published Oct 2026
Video
How to Jumpstart a Robotic Practice in Pediatrics with Dr. Juan Gurria
99 min · Published Oct 2026
Video
Update Course Rewind 2025: ECPR in Pediatric Cardiac Arrest with Drs. Juan Gurria & David Rothstein
2 min · Published Oct 2026
Podcast
Routine Anal Dilations After PSARP: Questioning a Decades-Old Practice
2 min · Published Nov 2026
Podcast
Pediatric Surgery Literature Updates: Lymphatic Malformations, G-Tube Complications, and Cryptorchidism Timing
4 min · Published Nov 2026
Podcast
Botox injection during Hirschsprung pull-through: evidence and technique considerations
1 min · Published Nov 2026
Podcast
Central line troubleshooting and vascular access preservation in pediatric patients
2 min · Published Nov 2026
Podcast
Colorectal Quiz Episode 50: Key Takeaways from the 16th European Pediatric Colorectal Conference
24 min · Published Nov 2026
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Nerve monitoring and risk stratification in pediatric thyroid surgery
6 min · Published Nov 2026
What the experts said
To diagnose acute pancreatitis, symptoms must match lab work and imaging findings
Serum lipase must be at least 3 times the upper limit of normal for diagnosis
CT is used to follow the progression of pancreatitis disease
MRI is the key imaging component for diagnosing pancreatitis
Pediatric pancreatitis patients are not alcoholics, not full of stones, or smokers
Pediatric pancreatitis presents as a similar pathologic problem to adult disease but comes from a different reason
Anatomic abnormalities from development in the biliary tree can cause strictures leading to pancreatitis
Traumatic injuries cause pancreatitis in children
Solid pseudopapillary neoplasms are seen frequently in pediatric pancreatitis
Neuroendocrine tumors can cause pancreatitis in children
Historically, idiopathic pancreatitis was a black box category after trauma, alcohol, drugs, and smoking were ruled out
Idiopathic pancreatitis is now known to be caused by genetic mutations
Cincinnati Children's has a running list of 1000 pediatric patients with pancreatitis
Over 1000 patients at Cincinnati Children's, 85% have genetic mutations
Cincinnati Children's tests for a panel of 10 genetic mutations
The PRSS1 mutation causes very aggressive pancreatitis attacks early in life
Children as young as 12-13 years old present with acute pancreatitis and acute recurrent pancreatitis from PRSS1 mutation
The PRSS1 gene affects trypsinogen
Genetic mutations causing pancreatitis can increase the risk of pancreatic cancer
Children diagnosed with genetic pancreatitis at 5 or 6 years old have hopefully 95 years of life remaining
The risk of pancreatic cancer in children with genetic pancreatitis is tremendous due to their long life expectancy
MRI with MRCP gives the best picture of the patient's ductal anatomy
In adults, alcohol and gallstones are the usual causes of pancreatitis
Causes of pancreatitis in children include anatomy, trauma, medications, and especially genetics
Cincinnati Children's has become the world's largest pediatric pancreatitis center
The PRSS1 gene mutation causes the pancreas to degrade itself