Characteristics of Transfusion and Association With Oncologic Outcomes in Hepatoblastoma Resection
hosted by Dr. Jill Kneroth · StayCurrentMD
Educational content from recorded physician discussions — not medical advice. Talk to your (or your child's) care team about your situation.
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What the experts said
It is not uncommon for a patient with hepatoblastoma to need a transfusion during resection
The study was multi-institutional and published in Pediatric Blood and Cancer in 2025
The study examined how intraoperative transfusion may affect recurrence and survival in hepatoblastoma resection patients
Of those transfused, the majority received red blood cells
Only 11% of transfused patients received platelets
Intraoperative blood transfusions had no effect on recurrence
Intraoperative blood transfusions were associated with increased death
There were instances of unnecessary blood transfusions
Patients who were transfused had higher post-op hemoglobin
Transfused patients still required more plasma and platelets postoperatively
The authors think that blood transfusions were mostly red blood cells, and that is what contributed to the post-op coagulopathy
The authors recommend more careful patient selection for intraoperative transfusions
The authors recommend a balanced transfusion approach