Commentary - Mowat-Wilson Syndrome in Hirschsprung: Something Special or Just a Generic Problem?

Abstract

The author comments on the recent paper by Cheng et al describing a series of MWS patients derived from a much larger series of HSCR patients. Children operated for HSCR with developmental delay suffer more difficulties than children without, but the literature varies on the outcomes associated with developmental delay such as Down syndrome and MWS. The author suggests that the degree of developmental delay has a bearing on outcome, and he further asks whether MWS has any particular features to make its prognosis different from other developmental delay syndromes associated with HSCR.

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