Aggressive Pursuit of No Evidence of Disease Status in Hepatoblastoma Improves Survival
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- Aggressive pursuit of no evidence of disease (NED) status significantly improves overall survival in hepatoblastoma patients.
- Both high-risk and non-high-risk hepatoblastoma patients benefit from achieving NED status.
- 82% of hepatoblastoma patients (41/50) were successfully rendered NED in this Cincinnati cohort.
- Event-free survival improved significantly when NED status was achieved, regardless of initial risk stratification.
- Complete surgical resection and chemotherapy should aim for NED rather than accepting residual disease in hepatoblastoma.
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Do you pursue no evidence of disease status in hepatoblastoma? Hi, I'm Cecilia Giquena from Cincinnati Children's Hospital and I think this is an article that you should know about. This is a retrospective observational study done in Cintu Children's Hospital from 2005 to 2021. And their aim was to examine the effect of aggressive pursuit of no evidence of disease status on overall survival and event free status. And what did they find? They had 50 patients with hepatoblastoma, and 41 were rendered for no evidence of disease. They found that overall survival and event free status were significantly improved in both high risk and non-high risk patients. So, it seems that pursuing no evidence of disease status is better for overall survival in hepatoblastoma patients. Stay tuned for more articles that you should know about.