The Morphing Bladder of PUV

And for the physicians in the audience there, you know, it is important to understand that the bladder will change from birth if you provide an optimal environment for it. So oftentimes when the bladder is so thick because the muscle has been overworked, it's been trying to contract against an obstruction of the postlethal valves. So those muscles are very, very thick, and it causes a functional obstruction of the ureter, and that's why the kidneys get damaged. But once we incise the valves and we start using um some medicines to try and soften up that bladder, these medicines are called anticholinergics. You may have, you've heard of the term Ditropan or Detrol. Those medicines soften up the bladder muscle and so now the ureter is no longer obstructed, but the pressure in the bladder might still be so high that it causes reflux. And then eventually as we continue to make that bladder healthier, we will have low pressures, a normal um muscle in the bladder, and then the urethro vesicle junction is functioning again, so there's no reflux, and that's gonna protect the kidneys also. So the bladder can go from one end to the other end and it can change in both directions and our job is to make sure that we're keeping it in the healthier range of that spectrum.