Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection.
pubmed.ncbi.nlm.nih.gov shows its articles on its own site.
Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Nov 2026 · 1 min read
In brief
In brief
This study investigates how H. pylori infection triggers PD-L1 expression on gastric epithelial cells through the Sonic Hedgehog signaling pathway. Understanding this early immune evasion mechanism may reveal new therapeutic targets for preventing H. pylori-associated gastric cancer development.
Written by the GCMD Library team from the article.
Statements in this article
Helicobacter pylori is the major risk factor for the development of gastric cancer.
The Sonic Hedgehog signaling pathway is an early response to H. pylori infection that is fundamental to the initiation of H. pylori-induced gastritis.
H. pylori induces programmed death ligand 1 (PD-L1) expression on gastric epithelial cells.