Article1 min read·Published Aug 2019Older

Weight loss after sleeve gastrectomy in developmentally delayed adolescents and young adults

Part of Adolescent Bariatric Surgery 39 items

pubmed.ncbi.nlm.nih.gov

Michael Helmrath

Background: Adolescent obesity is a significant factor in caring for patients with developmental delay (DD). Sleeve gastrectomy provides durable weight loss for teens with obesity but requires behavioral change that may not occur in patients with DD. Objectives: To determine whether patients with DD had similar weight loss and adverse outcomes to patients without a diagnosis of DD after sleeve gastrectomy. Setting: Academic children's hospital, United States. Methods: Patients with DD undergoing sleeve gastrectomy were matched to adolescents without DD. Chart review was performed to determine etiology and severity of DD, weight, and body mass index (BMI) change in each group at 3, 6, 9, and 12 months postoperatively. One-year emergency department visits, readmissions, and reoperations were reviewed. Results: Ten patients with DD and 44 patients without DD underwent sleeve gastrectomy between 2008 and 2017. Six patients with DD (60%) had mild cognitive impairment, 3 patients (30%) had moderate cognitive impairment, and 1 patient (10%) had severe cognitive impairment. Patients were 81.5% female, had a mean age of 17.3 years, and had a preoperative BMI of 48.6 kg/m2. Preoperative BMI was similar in the 2 groups, and percent BMI reduction at 1 year was -29% (95% confidence interval: -35 to -23) and -26% (95% confidence interval: -29 to -23) in groups with and without DD respectively (group by time interaction, P = .27). Conclusion: Adolescents with DD experience similar 1-year we

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Article · Aug 2019 · 1 min read

In brief

This matched cohort study demonstrates that adolescents with developmental delay achieve comparable weight loss outcomes to neurotypical peers one year after sleeve gastrectomy, with 29% versus 26% BMI reduction respectively. The findings challenge assumptions about behavioral change requirements and support bariatric surgery as a viable treatment option for obese adolescents across the cognitive spectrum.

Written by the GCMD Library team from the article.

Michael Helmrath

Statements in this article

Ten patients with developmental delay and 44 patients without developmental delay underwent sleeve gastrectomy between 2008 and 2017.
ResearchResults
Among patients with developmental delay, 60% had mild cognitive impairment, 30% had moderate cognitive impairment, and 10% had severe cognitive impairment.
ResearchResults
The study population was 81.5% female with a mean age of 17.3 years and a preoperative BMI of 48.6 kg/m2.
ResearchResults
Preoperative BMI was similar between patients with and without developmental delay.
ResearchResults
Percent BMI reduction at one year was -29% (95% confidence interval: -35 to -23) in patients with developmental delay and -26% (95% confidence interval: -29 to -23) in patients without developmental delay, with no significant difference between groups (P = .27).
ResearchResults
Adolescents with developmental delay experience similar one-year weight loss outcomes after sleeve gastrectomy compared to those without developmental delay.
ResearchConclusion