Article1 min read·Published Jan 2020Older

Weight Loss and Health Status 5 Years After Adjustable Gastric Banding in Adolescents

Part of Adolescent Bariatric Surgery 39 items

pubmed.ncbi.nlm.nih.gov

Michael Helmrath

Objective: This prospective cohort analysis describes changes in weight, cardiometabolic health, and weight-related quality of life (WRQOL) following adolescent LAGB. Methods: Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) collected demographic, anthropometric, micronutrient, cardiometabolic risk, and WRQOL data for 242 adolescents. Data through 5 years were analyzed for 14 participants who underwent LAGB with 2 patients lost to follow-up. Results: Participants (mean age 18.2 ± 0.4 years) were mostly female (86%) and white (71%) with a median body mass index (BMI) of 48.7 kg/m2 (45.5-54.1). Preoperatively, 100%(13/13), 62%(8/13), 57%(8/14), and 7%(1/14) had elevated high sensitivity C-reactive protein (hs-CRP), dyslipidemia, elevated blood pressure (EBP), and type 2 diabetes (T2D), respectively. At 5 years, mean BMI decreased by 3.3% (51.0 vs. 49.3 kg/m2, p = 0.6), 43%(6/14) had BMI values exceeding baseline and 21% (3/14) underwent band removal. Postoperative prevalence of hs-CRP, dyslipidemia, EBP, and T2D was 45% (4/11), 36% (5/11), 33% (4/12), and 0% (0/11), respectively. Conclusion: Adolescents undergoing LAGB experienced modest initial weight loss and improvements in cardiovascular risk factors with later weight regain and frequent need for band removal. Despite the small sample size, this prospective study highlights long-term outcomes with high rates of participant retention over time. Clinical Trial Registration: NCT00465829.

pubmed.ncbi.nlm.nih.gov shows its articles on its own site.

Read the article on pubmed.ncbi.nlm.nih.gov ↗

Article · Jan 2020 · 1 min read

In brief

Five-year follow-up of 14 adolescents who underwent laparoscopic adjustable gastric banding reveals modest weight loss with frequent regain and 21% requiring band removal. Despite limited weight reduction, participants showed improvements in cardiometabolic markers including resolution of type 2 diabetes and reductions in dyslipidemia and elevated blood pressure.

Written by the GCMD Library team from the article.

Michael Helmrath

Statements in this article

The Teen-LABS cohort included 242 adolescents who underwent bariatric surgery, of whom 14 received laparoscopic adjustable gastric banding.
ResearchMethods
Participants had a mean age of 18.2 years, 86% were female, 71% were white, and median baseline BMI was 48.7 kg/m² (IQR 45.5–54.1).
ResearchResults
At baseline, 100% of participants had elevated high-sensitivity C-reactive protein, 62% had dyslipidemia, 57% had elevated blood pressure, and 7% had type 2 diabetes.
ResearchResults
At 5 years after LAGB, mean BMI decreased by 3.3% from 51.0 to 49.3 kg/m² (p = 0.6).
ResearchResults
At 5 years, 43% of participants had BMI values exceeding their baseline.
ResearchResults
Twenty-one percent of participants required band removal by 5 years postoperatively.
ResearchResults
At 5 years, the prevalence of elevated high-sensitivity C-reactive protein was 45%, dyslipidemia 36%, elevated blood pressure 33%, and type 2 diabetes 0%.
ResearchResults
Adolescents undergoing LAGB experienced modest initial weight loss and improvements in cardiovascular risk factors, followed by later weight regain and frequent need for band removal.
ResearchConclusion