Article1 min read·Published Dec 2020Older

Delay in achieving enteral autonomy and growth outcomes in very low birth weight infants with surgical necrotizing enterocolitis

Part of Short Bowel Syndrome & Intestinal Failure 8 items

pubmed.ncbi.nlm.nih.gov

Michael Helmrath

Objective: To understand the nutritional intake and growth outcomes of very low birth weight infants with surgical necrotizing enterocolitis (NEC). Study Design: In a retrospective cohort study, linear mixed models were used to compare growth outcomes from birth to 24 months corrected age for very low birth weight (VLBW) infants with surgical NEC to those with spontaneous intestinal perforation (SIP). Kaplan-Meier curves were developed to demonstrate the duration of parenteral nutrition (PN) use. Result: Height differed by surgical NEC and SIP over time (interaction p = 0.03). Surviving infants with surgical NEC had lower head circumference z-scores at 24 months. Of infants surviving surgical NEC, 71% received PN for >60 days after diagnosis. Conclusion: The majority of infants with surgical NEC have a delay in achieving enteral autonomy. There was a difference in linear catch-up growth over time between infants with SIP and surgical NEC at 24 months.

pubmed.ncbi.nlm.nih.gov shows its articles on its own site.

Read the article on pubmed.ncbi.nlm.nih.gov ↗

Article · Dec 2020 · 1 min read

In brief

This retrospective study of VLBW infants shows that surgical NEC significantly delays enteral autonomy, with 71% requiring parenteral nutrition beyond 60 days post-diagnosis. Compared to spontaneous intestinal perforation, surgical NEC patients demonstrated impaired linear growth and reduced head circumference at 24 months corrected age.

Written by the GCMD Library team from the article.

Michael Helmrath

Statements in this article

Height differed significantly over time between very low birth weight infants with surgical necrotizing enterocolitis and those with spontaneous intestinal perforation (interaction p = 0.03).
Research
Surviving infants with surgical necrotizing enterocolitis had lower head circumference z-scores at 24 months corrected age compared to those with spontaneous intestinal perforation.
Research
71% of infants surviving surgical necrotizing enterocolitis received parenteral nutrition for more than 60 days after diagnosis.
Research
The majority of infants with surgical necrotizing enterocolitis have a delay in achieving enteral autonomy.
Research
There was a difference in linear catch-up growth over time between infants with spontaneous intestinal perforation and surgical necrotizing enterocolitis at 24 months corrected age.
Research