Educational content from recorded physician discussions — not medical advice. Always talk to your child's care team about your child's situation.
Content of this collection
An Introduction to Pediatric Surgical Oncology
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Authored article introducing pediatric surgical oncology concepts and management
article · Oct 2026
What is new in pediatric surgical oncology?
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Purpose Of Review: As pediatric oncology has become more complex, designing and maintaining pediatric surgical protocols require greater expertise. The primary purpose of this review is to summarize the changes in protocols and new study fi
article · Oct 2026
Fertility consults should be offered to all patients undergoing any chemotherapy, with risk assessment based on therapy type. — Roshni Dasgupta, Evolution of pediatric surgical oncology as a subspecialty · 22:12
Development and Implementation of a Global Pediatric Oncology Surgery Fellowship Curriculum: A Consensus-Driven and Collaborative Effort to Address Workforce Challenges
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Background/Purpose: Pediatric cancer is a major global health challenge, with an estimated 400,000 new cases diagnosed each year. Access to specialized surgical care is particularly limited in low- and middle-income countries (LMICs), where
article · Oct 2026
Evolution of pediatric surgical oncology as a subspecialty
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This inaugural edition of the Surgical Oncology Clinics Podcast features discussion of the April 2021 issue on "Pediatric Cancer". Guest Editor Dr. Roshni Dasgu
podcast26:59 · Oct 2026
Pediatric Oncology, An Issue of Surgical Oncology Clinics of North America
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Pediatric Oncology, An Issue of Surgical Oncology Clinics of North America ... - Google Books Sign in Hidden fields Books Try the new Your Library After November 18, 2026, you'll no longer be able to manage books in Classic My Library. Visi
article · Oct 2026
Pediatric Cancer, An Issue of Surgical Oncology Clinics of North America, E-Book
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This issue of Surgical Oncology Clinics, guest edited by Dr. Roshni Dasgupta, is devoted to Pediatric Cancer. Dr. Dasgupta has assembled expert authors to review the following topics: Management of Neuroendocrine Cancer and GIST in Pediatri
article · Oct 2026
Developing the research roadmap together: a report from the patient-centered outcome research institute (PCORI) and pediatric surgical oncology research collaborative (PSORC)
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OBJECTIVE: Patient-Centered Outcomes Research (PCOR) and Comparative Effectiveness Research (CER) focusing on pediatric cancer surgery are insufficient. To address this need, the authors aimed to create an evidence-based PCOR agenda for chi
article · Oct 2026
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Evolution of pediatric surgical oncology as a subspecialty
Pediatric cancer remains one of the top causes of death in children despite advances over the last several decades.
Host summaryTim Pollock summarizes what Dr. Roshni Dasgupta said — not the host's own clinical position1:19 ↗
Specific focus on pediatric oncology has only been established over the last 50 years.
Host summaryTim Pollock summarizes what Dr. Roshni Dasgupta said — not the host's own clinical position1:27 ↗
Surgical oncology has become a clear subspecialty within pediatric surgery.
Host summaryTim Pollock summarizes what Dr. Roshni Dasgupta said — not the host's own clinical position1:36 ↗
Changes in molecular and genetic profiling of tumors has caused a paradigm change in surgical oncology, particularly in pediatrics where biological considerations affect treatment pathways and prognostication.
clinicalRoshni Dasgupta2:54 ↗
Renal tumors are the second most common abdominal tumor in the pediatric population, behind only neuroblastoma.
Host summaryTim Pollock summarizes what Dr. Roshni Dasgupta said — not the host's own clinical position4:18 ↗
Wilms tumors generally present in children under the age of 4, usually with an asymptomatic palpable mass often found during a well-child check.
clinicalRoshni Dasgupta4:55 ↗
Imaging paradigm for suspected Wilms tumor starts with ultrasound, followed by CT or MRI depending on tumor appearance and genetic predispositions.
clinicalRoshni Dasgupta5:12 ↗
In Wilms tumor, metastatic disease alone is not a contraindication to primary surgical resection if the local stage appears resectable, unlike in other pediatric cancers.
clinicalRoshni Dasgupta5:50 ↗
Loss of heterozygosity at 1P and 16Q are poor prognostic factors in Wilms tumor, occurring in about 5% of patients and requiring more intensive therapy.
clinicalRoshni Dasgupta6:14 ↗
Gain of 1Q occurs in about 30% of Wilms tumor patients and requires more intensive therapy.
clinicalRoshni Dasgupta6:34 ↗
Patients under age 2 with Wilms tumors under 550g can be treated with surgery alone without chemotherapy, avoiding late effects.
clinicalRoshni Dasgupta6:44 ↗
In North America, Wilms tumor patients are typically operated on upfront, whereas in Europe the protocols favor giving chemotherapy first to shrink tumors.
clinicalRoshni Dasgupta8:14 ↗
In North America, neoadjuvant chemotherapy for Wilms tumor is given to patients with very high risk of rupture or extensive caval metastasis.
clinicalRoshni Dasgupta8:27 ↗
Genetic data (loss of heterozygosity at 1P and 16Q) has led to increased therapy intensity but does not dictate surgical management, which is primarily based on anatomical factors.
clinicalRoshni Dasgupta9:10 ↗
Patients with Wilms tumor have over 90% survival when taking all comers, so the focus has shifted to therapy reduction and preventing late effects.
epidemiologicalRoshni Dasgupta9:36 ↗
About two-thirds of liver tumors in children are malignant.
epidemiologicalRoshni Dasgupta10:57 ↗
Infantile hemangiomas in children are different from adult liver hemangiomas (which are venous malformations); infantile hemangiomas proliferate and then involute.
clinicalRoshni Dasgupta11:00 ↗
Hepatoblastoma is the most common liver tumor in children, usually presenting under age 3.
epidemiologicalRoshni Dasgupta11:24 ↗
Children with hepatoblastoma generally do not have underlying liver disease, unlike adults with hepatocellular carcinoma who often have cirrhosis or chronic liver conditions.
clinicalRoshni Dasgupta12:00 ↗
Most hepatoblastoma patients have elevated AFP, and there is characteristic diagnostic imaging for hepatoblastoma.
clinicalRoshni Dasgupta13:20 ↗
Hepatoblastoma is staged using the PRETEXT staging system, done prior to any treatment, with annotation factors for vascular involvement, hepatic vein involvement, metastatic disease, and multifocality.
clinicalRoshni Dasgupta13:30 ↗
PRETEXT 1 and 2 hepatoblastoma patients are treated upfront with surgical resection; these have a nice margin around hepatic veins and are easily resectable.
clinicalRoshni Dasgupta13:55 ↗
PRETEXT 3 and 4 hepatoblastoma patients with multifocal disease are treated with chemotherapy upfront, then surgical resection after 2-3 cycles.
clinicalRoshni Dasgupta14:06 ↗
Hepatoblastoma patients with multifocal disease who have minimal response after two cycles of chemotherapy are referred to transplant centers, as transplant is a viable option.
clinicalRoshni Dasgupta14:19 ↗
Pediatric tumors are rare—the most common types have between 700-800 cases per year, orders of magnitude less than adult cancers like breast or lung cancer.
epidemiologicalRoshni Dasgupta15:24 ↗
International data sharing through cooperative groups is integral to studying pediatric tumors, understanding outcomes, and developing common treatment paradigms across surgery, chemotherapy, and radiation.
clinicalRoshni Dasgupta15:40 ↗
The Pediatric Hepatic International Tumor Trial (PHITT) includes European and Japanese colleagues, does central radiological reviews, and has improved patient care while generating new research questions.
clinicalRoshni Dasgupta16:39 ↗
Minimally invasive surgery in pediatric oncology has been primarily diagnostic, including thoracoscopic biopsies of lung nodules and is frequently used for ovarian tumors.
clinicalRoshni Dasgupta17:59 ↗
A new study is planned comparing thoracoscopy versus thoracotomy in patients with osteosarcoma.
clinicalRoshni Dasgupta18:20 ↗
Robot use in pediatric oncology is limited by patient body size; in patients weighing 4-5 kg, robots are difficult to use due to port size constraints.
clinicalRoshni Dasgupta18:35 ↗
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