Educational content from recorded physician discussions — not medical advice. Always talk to your child's care team about your child's situation.
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Clinical guideline for the diagnosis and treatment of fibrolamellar carcinoma.
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Hepatology (Baltimore, Md.) · 2026
article · Oct 2026
DNAJB1-PKAc Fusion Kinase1 item
DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways
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Background and Aims: Hepatoblastoma (HBL) and fibrolamellar hepatocellular carcinoma (FLC) are the most common liver malignancies in children and young adults. FLC oncogenesis is associated with the generation of the fusion kinase, DNAJB1-P
article · Oct 2026
β-Catenin-Cohesin Axis2 items
β-Catenin-Cohesin Ring-CEGRs/ALCDs Axis Activation Contributes to the Development of Hepatoblastoma and Fibrolamellar HCC
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Unlabelled: The pediatric and adolescent liver cancers, hepatoblastoma (HBL) and fibrolamellar hepatocellular carcinoma (FLC), respectively, are dangerous diseases requiring aggressive surgery, when feasible, and nontargeted toxic chemother
article · Oct 2026
β-catenin cancer-enhancing genomic regions axis is involved in the development of fibrolamellar hepatocellular carcinoma
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Fibrolamellar hepatocellular carcinoma (FLC) is a disease that occurs in children and young adults. The development of FLC is associated with creation of a fusion oncoprotein DNAJB1-PKAc kinase, which activates multiple cancer-associated pa
article · Oct 2026
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