Podcast Library

Clinical translation of tissue-engineered oesophageal grafts: are patients ready for us?

Abstract Purpose We sought to engage with expert patient/carers to understand attitudes towards use of tissue engineering (TE) for long-gap...

Utility of preoperative prophylactic antibiotics for preventing surgical site infections in children with infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis

Abstract Purpose The aim of this study was to determine the utility of prophylactic antibiotics before pyloromyotomy for the prevention of...

GAPS Phase III: incorporation of capacity based weighting in the global assessment for pediatric surgery

Abstract Introduction The Global Assessment for Pediatric Surgery (GAPS) tool was developed to enhance pediatric surgical care in Low- and...

Laparoscopic Cecostomy Placement for Antegrade Enema Access in the Pediatric Population

Use of the appendix for an antegrade continence enema (ACE) is not always possible. Various methods exist for creating cecostomy tubes, including...

Tracheal Allotransplantation to Deliver Growing Airway Implants for Infants and Children

The first successful organ transplantation was performed by Dr. Joseph Murray at The Peter Bent Brigham Hospital in 1954 [1]. After the...

Antibiotic Prophylaxis for Elective Pediatric Laparoscopic Cholecystectomies

The Surgical Infection Society (SIS) guidelines recommend against the use of surgical antibiotic prophylaxis (SAP) for low-risk patients...

Using shock index, pediatric age adjusted (SIPA) to predict prolonged length of stay in perforated appendicitis: a retrospective review

Abstract Purpose Hospital length of stay (LOS) following admission for appendicitis is difficult to predict. Shock index, pediatric age adjusted...

Partial Splenectomy Versus Total Splenectomy in Sickle Cell Disease: A Systematic Review and Meta-Analysis

Sickle cell disease (SCD) patients encounter various complications, such as acute splenic sequestration crisis and hypersplenism that may require...

Outcome of Injection Sclerotherapy With Doxycycline in Lymphatic, and Veno-lymphatic Malformation in Children: A Single Centre Experience

Lymphatic malformations (LMs) and Veno-lymphatic malformations (VLMs) are congenital slow flow vascular malformations. Intralesional sclerotherapy...

Antibiotic Management After Neonatal Enteric Operations in US Children's Hospitals

There are few evidence-based guidelines for perioperative antibiotic management in neonates who undergo enteric operations. We sought to assess...

Contemporary use of fibrinolytics in the management of pediatric empyema

Abstract Background This study seeks to investigate the contemporary use and effectiveness of fibrinolysis as a first-line option in pediatric...

Dissecting the dynamics of cell death pathways in Hirschsprung’s disease: a comparative analysis of viable and non-viable cells under proinflammatory conditions

Abstract Purpose The present study explores the dynamics of cell death in Hirschsprung’s disease (HSCR) and control (CO) groups under inflammatory...

Clean Intermittent Catheterisation via a Mitrofanoff Is Superior to Long Term Suprapubic Catheters for Bladder Drainage

Some children require long-term drainage of the bladder but do not tolerate clean intermittent catheterisation (CIC) urethrally. We aimed to...

Trends and outcomes in pediatric laparoscopic appendectomy: a NSQIP-P analysis of same-day discharge and readmission rates

Abstract Purpose Practice patterns of same-day discharge for pediatric laparoscopic appendectomy for non-perforated appendicitis are not...

Promoting application of enhanced recovery after surgery protocols during perioperative localized abdominal and thoracic neuroblastomas

Abstract Aim To investigate the safety and efficacy of the application of enhanced recovery after surgery (ERAS) protocols in the perioperative...

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Table of Contents

Survival rate changes in children with congenital diaphragmatic hernia over the past three decades: a nationwide, population-based prospective nested case–control study

Abstract Purpose The survival rate (SR) for neonates born with congenital diaphragmatic hernia (CDH) remains high. Our aim was to investigate the...

A retrospective analysis of alimentary tract duplications in pediatric patients: a 14-year single-center experience

Abstract Purpose Alimentary tract duplications (ATDs) are rare congenital lesions often associated with anomalies such as spinal, urinary and GI...

Isolated laparoscopic extra-vesical ureteric reimplantation (I-LEVUR) for upper moiety ectopic ureter without lower moiety vesicoureteric reflux

Abstract Purpose To evaluate the feasibility and outcomes of isolated laparoscopic extra-vesical ureteric reimplantation (I-LEVUR) for upper...

Long-term Survival of Bladder Augmentation is Influenced by its Shape and Mucosal Lining

Bladder augmentation in the UK has been largely by enterocystoplasty or ureterocystoplasty (UC). Ileocystoplasty can be simple patch placement...

Comprehensive meta-analysis of surgical procedure for congenital diaphragmatic hernia: thoracoscopic versus open repair

Soichi Shibuya, Irene Paraboschi, Stefano Giuliani, Takafumi Tsukui, Andreea Matei, Maricarmen Olivos, Mikihiro Inoue, Simon A Clarke, Atsuyuki...

Enhanced Recovery After Surgery for Pediatric Abdominal Tumor Resections: A Prospective Multi-institution Study

Enhanced recovery after surgery (ERAS) protocols are multi-disciplinary approaches to standardize perioperative care. This is the first...

QUAD #18: Vascular Rings & Aortic Uncrossing with Dr. Carl Backer

In this video, Dr. Carl Backer, renowned pediatric surgeon, shares insights on vascular rings and aortic uncrossing at Cincinnati Children's...

Medical Costs of Patients Undergoing Esophageal Atresia Repair are Mainly Influenced by Associated Malformations

Background Esophageal atresia (EA) is a rare disease requiring surgical repair, usually within the first days of life. Patients with EA require...

STAT trial: stoma or intestinal anastomosis for necrotizing enterocolitis: a multicentre randomized controlled trial

Abstract Purpose The STAT trial is a multicenter randomized controlled trial in 12 centers worldwide aiming to determine the most effective...

How Many Lymph Nodes are Enough in Paratesticular Rhabdomyosarcoma?

Treatment strategies for paratesticular rhabdomyosarcoma (PT RMS) are based on stage, which requires accurate lymph node (LN) evaluation. Previous...

The efficacy of partial versus total splenectomy in the treatment of hereditary spherocytosis in children: a systematic review and meta-analysis

Abstract Objective To explore the comparative postoperative efficacy of partial splenectomy (PS) and total splenectomy (TS) in the treatment of...

Long-term Outcomes of Botulinum Toxin Injection Into the External Anal Sphincters: An Effective New Treatment of Chronic Functional Constipation in Children

Botulinum toxin (BT) is a well-recognised treatment of chronic functional constipation (FC) and soiling refractory to medical treatment. The aims...

Usefulness of lateral-anteroposterior dimeter ratio in patients with tracheomalacia associated with esophageal atresia

Abstract Purpose Tracheomalacia (TM) is commonly associated with esophageal atresia (EA) and compression by the brachiocephalic artery is a factor...

Complication Rates and Variability in Gastrojejunostomy Tube Usage in Infants and Children

Gastrojejunostomy tube (GJT) placement is commonly performed for enteral access and post-pyloric feeding in children with gastric feeding...

Dipeptidyl peptidase IV inhibitors reduce hepatic fibrosis and lipid accumulation in rat intestinal failure-associated liver disease models

Abstract Purpose This study aimed to investigate the effectiveness of dipeptidyl peptidase IV inhibitors (DPP4-I) against liver damage, especially...

Physical Activity Levels in Children with Esophageal Atresia and Congenital Heart Disease: A Comparative Multicenter Study

Aim of the Study Esophageal atresia (EA) is associated with impaired motor development, cardiopulmonary function, and physical activity (PA)....

Features of recurrence and contralateral metachronous inguinal hernia (CMIH) in the patients underwent laparoscopic percutaneous extraperitoneal closure (LPEC) for pediatric inguinal hernia

Abstract Purpose Recurrence and contralateral metachronous inguinal hernia (CMIH) are important postoperative complications in patients with...

Sex-specific differences in the severity of pulmonary hypoplasia in experimental congenital diaphragmatic hernia and implications for extracellular vesicle-based therapy

Abstract Purpose Amniotic fluid stem cell extracellular vesicles (AFSC-EVs) hold regenerative potential to treat hypoplastic lungs secondary to...

Angiopoietin-1 attenuates lipopolysaccharide-induced endotoxemia in a Hirschsprung’s disease murine model by improving intestinal vascular integrity: implications for treating postoperative Hirschsprung-associated enterocolitis

Abstract Purpose Angiopoietin-1 (Ang1) mitigates inflammation as a proangiogenic growth factor. Action of Ang1 on lipopolysaccharide (LPS)-induced...