Transamniotic Delivery of Hematopoietic Stem Cells Genetically Modified to Carry a Human Hemoglobin Subunit Beta Gene (HBB) in a Healthy Rodent Model
Author / Expert
Kamila Moskowitzova, Emily M. Scire, Ina Kycia, Tanya T. Dang, Beatriz S. Bechara, Eva Zacharakis, Ayaka Aihara, Yash V. Shroff, David Zurakowski, Dario O. Fauza
Topic overview
We sought to determine whether transamniotic stem cell therapy (TRASCET) could be a viable alternative for the fetal administration of genetically modified hematopoietic stem cells (HSCs) carrying a human hemoglobin subunit beta gene (hHBB) in a healthy syngeneic rat model.
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