Comparative Study between Autologous Platelet-Rich Fibrin Membrane and Local Flaps as Intervening Layer in Management of Distal Hypospadias

Space: StayCurrentMD Author: Ahmed M. Elnashar, Mohamed Albishbishy, Hesham Sheir, Moustafa Elayyouti, Mohamed Elsherbiny, Mohamed Elzohiri, Mohamed El-Ghazaly, Adham Elsaied Published:

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Ahmed M. Elnashar, Mohamed Albishbishy, Hesham Sheir, Moustafa Elayyouti, Mohamed Elsherbiny, Mohamed Elzohiri, Mohamed El-Ghazaly, Adham Elsaied

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The most frequent complication following hypospadias correction is fistula formation. Recently, fibrin glue has been employed as a 2nd layer covering the urethroplasty resulting in a reduction in the incidence of fistulas. Platelet rich fibrin (PRF) is an autologous growth factor - rich source. Although the authors recommend the use of additional layers in hypospadias correction, there remains a controversy. In a trial to address this issue, our research was conducted to compare the accessibility of urethroplasty coverage using PRF to traditional local flaps, aiming to prevent fistula formation in hypospadias repair.

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