Distraction Enterogenesis Induces Desert Hedgehog in the Lengthened Murine Colon

Space: StayCurrentMD Author: Siavash Shariatzadeh, Arshia Tofang Sazi, James C.Y. Dunn Published:

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Siavash Shariatzadeh, Arshia Tofang Sazi, James C.Y. Dunn

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Distraction enterogenesis lengthens the intestine through applied mechanical stress. The Hedgehog pathway (Hh) is responsible for intestinal tract development and directing the multi-layer patterning of the intestinal lumen. This study investigates the alteration in the principal components of this pathway in spring-mediated colonic lengthening.

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