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Assessing the Diagnostic Accuracy of TI-RADS in Pediatric Thyroid Nodules: A Multi-institutional Review

Space: StayCurrentMD Author: Shachi Srivatsa, Ameer Al-Hadidi, Joseph Stanek, Kyle Horvath, Lauren Parsons, Claudia Martinez-Rios, Amanda Hopp, Samuel Engle, Matthew Plunk, Gali Shapira-Zaltsberg, Sapna Nagar, Sean Masters, Sayf Al-Katib, Rennard Tucker, Lamya A. Atweh, Summit Shah, Published:

Author / Expert

Shachi Srivatsa, Ameer Al-Hadidi, Joseph Stanek, Kyle Horvath, Lauren Parsons, Claudia Martinez-Rios, Amanda Hopp, Samuel Engle, Matthew Plunk, Gali Shapira-Zaltsberg, Sapna Nagar, Sean Masters, Sayf Al-Katib, Rennard Tucker, Lamya A. Atweh, Summit Shah,

Topic overview

Thyroid nodules are uncommon in children and adolescents but carry an increased risk of malignancy when present. The Thyroid Imaging Reporting and Data System (TI-RADS) is an adult-validated ultrasound-based risk assessment providing a prediction of malignant potential for thyroid nodules, thereby guiding recommendations for fine needle aspiration biopsy (FNAB). Minimal data exist regarding the applicability of TI-RADS to predict malignancy in pediatric thyroid nodules. This study aims to analyze the performance of TI-RADS for children and adolescents with thyroid nodules, hypothesizing that applying TI-RADS criteria would improve accuracy and reduce the number of recommended FNAB compared to American Thyroid Association (ATA) size criteria alone.

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