CAMK2G Promotes Neuronal Differentiation and Inhibits Migration in Neuroblastoma

Space: StayCurrentMD Author: Yujie Ma, Cong He, Weihong Lin, Jing Wang, Chaoliang Xu, Deshen Pan, Zuopeng Wang, Wei Yao, Rui Dong, Deshui Jia, Kai Li Published:

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Yujie Ma, Cong He, Weihong Lin, Jing Wang, Chaoliang Xu, Deshen Pan, Zuopeng Wang, Wei Yao, Rui Dong, Deshui Jia, Kai Li

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Neuroblastoma (NB) originates from differentiation arrest of sympathoadrenal progenitors in the neural crest. It is necessary to reveal the differentiation mechanism of NB. Previously, we reported that Purkinje cell protein 4 (PCP4) is a well-differentiated marker of NB tissues. Herein, we explored the underlying mechanism of PCP4 induced differentiation in order to find better treatment options for patients.

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