Early Ventilator Management for Infants With Congenital Diaphragmatic Hernia: Impact of a Standardized Clinical Practice Guideline
Author / Expert
Katrin C. Lichtsinn, Joseph T. Church, Paul K. Waltz, Abeer Azzuqa, Jacqueline Graham, Jennifer Troutman, Runjia Li, Burhan Mahmood
Topic overview
Infants with congenital diaphragmatic hernia (CDH) experience high morbidity and mortality due to pulmonary arterial hypertension and hypoplasia. Mechanical ventilation is a central component of CDH management. Our objective was to evaluate the impact of a standardized clinical practice guideline (implemented in January 2012) on ventilator management for infants with CDH, and associate management changes with short-term outcomes, specifically extracorporeal membrane oxygenation (ECMO) utilization and survival to discharge.
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