Letter to the Editor in Response to: Comparing Efficacy of Different Regional Analgesia Methods for Pediatric Laparoscopic Cholecystectomy
Topic overview
This correspondence critiques methodology in a comparative study of regional analgesia techniques for pediatric laparoscopic cholecystectomy. The authors question the sample size calculation approach used to evaluate postoperative opioid consumption and analgesic efficacy between TAP blocks and local wound infiltration.
Key takeaways
- Study compared TAP block vs local infiltration for pain control in pediatric laparoscopic cholecystectomy
- Primary outcome was opioid consumption, but sample size calculated using binary secondary outcomes
- Methodological concern: mismatch between continuous primary outcome and binary sample size calculation may affect study power
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How to cite: GlobalCastMD. Letter to the Editor in Response to: Comparing Efficacy of Different Regional Analgesia Methods for Pediatric Laparoscopic Cholecystectomy. GlobalCastMD Medical Library. 2024-01-29. https://library.globalcastmd.com/article/8243
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