Current epidemiology and antenatal presentation of posterior urethral valves: Outcome of BAPS CASS National Audit

Space: StayCurrentMD Author: Ewan Brownlee, Ruth Wragg, Andy Robb, Harish Chandran, Marian Knight, Liam McCarthy, On behalf of BAPS-CASS Published:

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Ewan Brownlee, Ruth Wragg, Andy Robb, Harish Chandran, Marian Knight, Liam McCarthy, On behalf of BAPS-CASS

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Abstract

Aim

Posterior urethral valves (PUVs) are the most common cause of congenital bladder outlet obstruction (BOO) in boys and end-stage renal failure (ESRF) in childhood. In the 1980s, 1 in 4000 boys had PUV. Presentation was 1/3 antenatal/neonatally, 1/3 postnatal, 1/3 late (>1 year). This study aimed to describe the current proportions in a contemporary cohort.

Methods

A national audit (BAPS CASS) of referrals in the UK and Ireland of boys diagnosed with suspected or confirmed PUV in a year was conducted. National registration data provided the male birth-rate. Data were presented as number (%), analysed by Mann–Whitney U-test and Chi-square test, with P 

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