miR-375-3p targets YWHAB to attenuate intestine injury in neonatal necrotizing enterocolitis

This molecular study demonstrates that miR-375-3p, elevated in breastfed neonates, protects against necrotizing enterocolitis by targeting YWHAB protein to reduce intestinal epithelial cell apoptosis and inflammation. The research provides mechanistic insight into breastfeeding's protective role in NEC and identifies potential therapeutic targets for this devastating neonatal condition.