Volume and function of the operated kidney after nephron-sparing surgery for unilateral renal tumor

Space: StayCurrentMD Author: Silvia Ceccanti, Francesco Cozzi, Alice Cervellone, Augusto Zani, Denis A. Cozzi Published:

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Silvia Ceccanti, Francesco Cozzi, Alice Cervellone, Augusto Zani, Denis A. Cozzi

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Abstract

Aim

We sought to assess the magnitude of functional decline and the natural history of the operated kidney residual function after zero-ischemia nephron-sparing surgery (Z-NSS) in children with unilateral renal tumor (URT).

Patients and methods

50 children were treated for URT at our surgical unit between 1992 and 2016. Of these 12 who underwent Z-NSS were available for the current analysis. Operated kidney function was assessed by 99mTc-dimercapto-succinic acid (DMSA) renal scintigraphy. Operated kidney volume was assessed by renal ultrasonography.

Results

A positive correlation between split renal function and split renal volume was found (P = 0.001). The subset of patients with ≥40% preservation of operated kidney function/volume (OKF/V) had no-time dependent changes during adolescence. The subset of patients with 80% follow-up and all patients enrolled at same time point in disease.

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