No Tissue Expression of KRAS or BRAF Mutations in 61 Adult Patients Treated for Esophageal Atresia in Early Childhood

Long-term follow-up study of 61 adults treated for esophageal atresia in childhood found no KRAS or BRAF mutations despite high rates of gastroesophageal reflux and Barrett's changes. Results suggest these mutations may not be useful early markers for malignant transformation in this population.