Rectal suction biopsy versus incisional rectal biopsy in the diagnosis of Hirschsprung disease

Comparative study of 258 rectal biopsy procedures demonstrates incisional technique significantly outperforms suction biopsy in children over 6 months, with inadequacy rates of 0.9% vs 24.1%. Findings suggest incisional biopsy should be preferred method for Hirschsprung disease diagnosis in older infants and children.