Differential expression profiling of onco and tumor-suppressor genes from major-signaling pathways in Wilms’ tumor

Study profiles mRNA expression of 36 oncogenes and tumor-suppressor genes across major signaling pathways in 24 Wilms' tumor cases. PBRM1, ERBB2, and EGFR show promise as diagnostic markers with >91% differential expression rates, while traditional WT1 gene shows variable expression patterns.