Update Course Rewind: Pectus Excavatum 2021
Inside this episode
Kai, the Library's AI content creator,
listened to this episode and mapped who's speaking, the chapters,
key claims, and cases. Every item links to the exact moment in the
recording.
AI-enriched
Inside this episode
Who's speaking
- Ellen Ancisco — host
- Ellen Ancisco — host
- Sean Saint Peter — guest_expert
- Sean Saint Peter — guest_expert
- Victor Garcia — guest_expert
- Steven Rothenberg — guest_expert
- Todd Ponsky — guest_expert
- Todd Ponsky — guest_expert
- Speaker 9 — guest_expert
Chapters
- 0:00Introduction and Case Presentation — Hosts introduce the episode topic and present a 16-year-old male case with pectus excavatum (pectus index 5.5) and shortness of breath on exertion, setting up the discussion of perioperative pain control options.
- 1:57Cryoanalgesia for Pain Management — Discussion of cryoanalgesia technique, mechanism, and outcomes including one-day length of stay and dramatic reduction in opioid use. Concerns raised about lack of long-term safety data and FDA device approval requirements.
- 3:51Alternative Pain Management Approaches — Erector spinal catheters described as alternative achieving 2-day length of stay with reduced opioid requirements. Multimodal pain regimens discussed including gabapentin, methadone, clonidine, and non-pharmacologic approaches.
- 6:16Pain Management Summary — Hosts summarize the pain management options presented: cryoanalgesia with excellent results but unknown long-term effects, erector spinal catheters superior to epidurals, and multimodal regimens achieving 2-day stays.
- 7:22Nuss Procedure Technical Considerations — Discussion of bar length selection (shorter bars may be more stable), use of sternal elevators for safety, thoracoscopy, subxiphoid incisions, and surgeon preference regarding left-to-right versus right-to-left bar passage.
- 10:28Summary and Closing — Final summary of key points on pain management and surgical technique, followed by promotional content for the podcast and upcoming course.
Key claims
- 1:07In a randomized trial of 110 patients comparing epidural and PCA for pectus excavatum pain control, epidurals did not show superior efficacy. — Sean Saint Peter
- 1:32In a trial of cryotherapy for pectus excavatum with approximately 30 patients per group, patients went home on post-operative day one, leading to loss of equipoise. — Sean Saint Peter
- 1:57Cryoanalgesia uses cold temperatures to cause a conduction block, interrupting pain impulses to the brain. — Ellen Ancisco
- 2:10Cryoanalgesia technique involves placing camera on top and probe through bottom, counting down to the 4th rib and freezing underneath it for 2 minutes per rib, treating ribs 4 through 7. — Sean Saint Peter
- 2:29Cryoanalgesia should not be performed on rib 8 or below because it can cause abdominal wall paralysis. — Sean Saint Peter
- 2:37With cryoanalgesia, length of stay decreased from 4 days to 1 day. — Sean Saint Peter
- 2:46Cryoanalgesia dramatically reduced median morphine equivalents compared to previous pain management approaches. — Sean Saint Peter
- 3:04There are no long-term studies of cryoanalgesia outcomes in pectus excavatum repair. — Victor Garcia
- 3:24Medical devices and implants are not required to undergo clinical trials before market introduction, unlike drugs. — Victor Garcia
- 3:36FDA requires clinical trials with long-term results for medications before approval, but not for medical devices and techniques. — Ellen Ancisco
- 3:55A study of approximately 100 patients compared epidurals with erector spinal catheters for pectus excavatum pain control. — Victor Garcia
- 4:09Erector spinal catheters are placed by the pain team with ultrasound guidance, positioned adjacent to but not in the vertebral space. — Victor Garcia
- 4:19Erector spinal catheters remain in place for 5 days, with hospital stay of 2 days; catheters are removed by family on day 3 at home. — Victor Garcia
- 4:33Erector spinal catheters reduced opioid requirements both in-hospital and post-discharge, with 2-day hospital stays compared to 4-5 days with epidurals. — Victor Garcia
- 5:08After implementing cryoanalgesia, patients not only went home on day 2 or 3 but felt significantly better at discharge compared to previous pain management methods. — Steven Rothenberg
- 5:40Multimodal pain therapy components include Tylenol, NSAIDs, precedex for gentle wake-up, dexamethasone for post-anesthetic nausea, and ketamine to avoid opioids. — Todd Ponsky
- 5:55Non-pharmacologic pain management resources include child life specialists, mindfulness resources, and physical therapists. — Todd Ponsky
- 6:02Best multimodal therapy treatments include preoperative counseling, gabapentin pre- and post-operatively, methadone, clonidine, bowel regimen medications, and anti-emetics. — Todd Ponsky
- 6:19At Nebraska where Steve Rayner practices, length of stay is under 2 days and patients are off opioids by 1 week using multimodal pain management. — Todd Ponsky
- 6:39Bar flippage typically occurs early and is due to the bar sitting in an incorrect interspace, poor positioning, inadequate wrapping, or insufficient securing. — Sean Saint Peter
- 6:54The bar must sit in a comfortable position before securing or it will not remain stable; securing alone does not prevent flippage. — Sean Saint Peter
- 6:59Bar flippage is completely a surgical technique issue, not related to pain management method. — Steven Rothenberg
- 7:40Computational modeling by physics-minded surgeons showed that shorter flat bars have different stress point distribution compared to traditional U-shaped bars, with more pressure on the sternum making them more stable. — Todd Ponsky
- 8:19Sternal elevator is used in approximately 10% of cases, primarily in younger patients with really deep stiff pectuses to allow less tissue damage and better repair. — Steven Rothenberg
- 8:35Some surgeons use sternal elevator in every pectus excavatum case to eliminate guesswork and enable entry and exit at the same interspace. — Victor Garcia
- 8:59Safety techniques to avoid cardiac injury during bar passage include thoracoscopy, sternal elevator, vacuum bell in the operating room, or subxiphoid incision. — Sean Saint Peter
- 9:31Passing the bar from left chest to right chest is preferred by some surgeons because right-to-left passage points the introducer directly at the ventricle. — Speaker 9
- 10:12Bar passage direction (left-to-right versus right-to-left) is surgeon preference and likely does not make significant difference as long as the substernal space is well dissected and visualization is clear. — Sean Saint Peter
Cases discussed
- 0:3616-year-old male with pectus excavatum presenting with shortness of breath on exertion
Points of disagreement
- 3:01Use of cryoanalgesia for pectus excavatum pain management
- Sean Saint Peter: Cryoanalgesia provides superior outcomes with 1-day length of stay and dramatically reduced opioid use; equipoise was lost after seeing results.
- Steven Rothenberg: Initially skeptical but became convinced after 4 cases; outcomes are unbelievable despite concerns about long-term data.
- Victor Garcia: Agrees cryoanalgesia works but concerned about absence of long-term studies and potential for chronic neuropathic pain; prefers erector spinal catheters as alternative with known safety profile.
- 8:08Frequency of sternal elevator use
- Steven Rothenberg: Uses sternal elevator in about 10% of cases; thoracoscopy provides adequate visualization in most younger patients.
- Victor Garcia: Uses sternal elevator in every case to eliminate guesswork and ensure consistent safe passage at the same interspace.
Open questions
- What are the long-term outcomes and potential complications of cryoanalgesia, particularly regarding chronic neuropathic pain?
- What is the optimal bar length for pectus excavatum repair to balance stability and outcomes?
- Should sternal elevator be used routinely in all cases or selectively based on patient characteristics?
- Does the direction of bar passage (left-to-right versus right-to-left) affect safety or outcomes?
Cryoanalgesia for Pectus Repair: When One Postoperative Day Changes the Trial
The patient case from this episode, retold from presentation to outcome with the decisions made along the way.
Written by Kai from the episode transcript and reviewed before
publishing.
For the care team · Case narrative · AI-written, human-reviewed
Cryoanalgesia for Pectus Repair: When One Postoperative Day Changes the Trial
The Presentation
A 16-year-old male presented with exertional dyspnea and a pectus index of 5.5 1:57. He had no comorbidities. The plan was chest wall reconstruction, and the question was which perioperative pain strategy to use alongside multimodal analgesia.
The Decision Point
The team at Children's Mercy had been running a randomized trial comparing epidural to patient-controlled analgesia for postoperative pain control in pectus repair. Neither arm was performing well — length of stay remained stubbornly at four days 2:37. Thirty patients had been enrolled in each group when the investigators added a third arm: cryoanalgesia, a technique using cold temperatures to create a conduction block that interrupts pain impulses to the brain 1:57.
The first patient treated with cryoanalgesia went home on postoperative day one 2:37. At that point, as one of the discussants put it, equipoise was lost 2:37. The trial stopped. The question was whether to adopt the technique broadly, despite the absence of long-term safety data.
What They Did
The Children's Mercy team adopted cryoanalgesia as their standard approach. The technique is straightforward: under thoracoscopic visualization, a cryoprobe is applied to the underside of ribs 4 through 7 for two minutes per rib 2:25. Rib 8 and below are avoided due to risk of abdominal wall paralysis 2:29. The procedure added time to the operation, but the results were immediate and dramatic. Median length of stay dropped from four days to one 2:37, and median morphine equivalents fell sharply 2:46.
Not every center followed the same path. Cincinnati Children's adopted erector spinal catheters instead — ultrasound-guided catheters placed by the pain service, juxtaposed to but not within the vertebral space 4:09. Patients go home on postoperative day two with the catheters still in place; families remove them at home on day three, for a total catheter duration of five days 4:19. This approach also reduced opioid requirements both in-hospital and after discharge 4:33, though it did not match the single-day discharge achieved with cryoanalgesia.
A third center reported success with an aggressive multimodal regimen alone — preoperative counseling, gabapentin before and after surgery, methadone, clonidine, bowel regimen medications, and antiemetics 6:02 — achieving a length of stay under two days and opioid cessation by one week postoperatively 6:19.
The Unresolved Question
One discussant, initially skeptical of cryoanalgesia due to concerns about operative time and reports of neuralgia, adopted the technique after four cases and described the change as "unbelievable," adding, "I feel bad that I waited so long" [q7]. His observation was specific: "It's not just when they go home, it's how they feel when they go home" 5:08.
But another discussant remained cautious. Cryoanalgesia works, he acknowledged, but there are no long-term studies 3:04. Unlike drugs, medical devices and implants are not required to undergo clinical trials before market introduction 3:24. The concern is not whether the technique controls acute pain — that question has been answered — but whether it produces delayed complications that have not yet been captured in the literature. The outcome of this specific case was not discussed.
What the Case Changes
The judgment here is not about whether cryoanalgesia works for acute pain — the evidence for that is clear and consistent across centers. The judgment is about how much long-term safety data you require before adopting a technique that changes patient experience this profoundly. One discussant framed it as a need for a registry. The alternative approaches — erector spinal catheters and intensive multimodal regimens — offer intermediate results with more established safety profiles. The choice depends on how you weight immediate benefit against unknown long-term risk, and whether you believe a technique this effective can wait for data that may take years to accumulate.
Takeaways from this story
- Cryoanalgesia reduced pectus repair length of stay from 4 days to 1 day and dramatically cut opioid use compared to epidural or PCA
- Cryoprobe technique: 2 minutes per rib on ribs 4-7; avoid rib 8 or below due to abdominal wall paralysis risk
- Erector spinal catheters offer an alternative: 2-day hospital stay, catheters removed at home on day 3, reduced opioid needs
- No long-term cryoanalgesia studies exist; medical devices don't require clinical trials before market introduction unlike drugs
Topic overview
This podcast episode summarizes a 2021 pediatric surgery update course session on pectus excavatum repair, focusing on perioperative pain control and surgical technique variations. The discussion centers on cryoanalgesia as a pain management option that dramatically reduced length of stay to one day and opioid use, though long-term safety data remain absent. Alternative approaches include erector spinal catheters (2-day length of stay) and multimodal regimens achieving under 2-day stays. Technical considerations include bar length selection (shorter bars may be more stable), use of sternal elevators for safety, and surgeon preference regarding left-to-right versus right-to-left bar passage.
Key takeaways
- Cryoanalgesia reduced pectus excavatum LOS from 4 to 1 day and dramatically cut opioid use, but long-term safety data are absent. (2:37)
- Erector spinal catheters offer 2-day LOS with reduced opioid needs vs 4-5 days with epidurals; families remove catheters at home on day 3. (4:19)
- Multimodal pain regimens (gabapentin, methadone, clonidine, NSAIDs) achieve <2-day LOS with patients off opioids by 1 week post-op. (6:02)
- Bar flippage stems from incorrect interspace placement or poor positioning before securing, not pain management choice—technique is key. (6:39)
- Sternal elevator use (10% of cases or routinely) plus thoracoscopy/vacuum bell minimizes cardiac injury risk during substernal dissection. (8:19)
Keywords
Hashtags
Transcript
Click "Show Transcript" to view the full text (11694 characters)
Comments