ANTITHROMBIN SUPPLEMENTATION FOR PREVENTION OF VASCULAR THROMBOSIS AFTER PEDIATRIC LIVER TRANSPLANTATION
Author / Expert
Maria Hukkinen, Michela Wong, Zeynep Demir, Radhia Hadj Salem, Dominique Debray, Sylvain Renolleau, Samira Sissaoui, Florence Lacaille, Muriel Girard, Mehdi Oualha, Stefania Querciagrossa, Monique Fabre, Cecile Lozach, Rozenn Clement, Dominique Lasne, Del
Topic overview
After liver transplantation (LT), synthesis of coagulation factors by the graft recovers faster for pro-thrombotic than anti-thrombotic factors, resulting in a potential pro-thrombotic imbalance. We studied the thrombotic and hemorrhagic complications in our pediatric LT series, providing supplementation of fresh frozen plasma (FFP) and/or antithrombin (AT) in the prophylactic antithrombotic regimen.
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