Yes-associated protein is dysregulated during nitrofen-induced hypoplastic lung development due to congenital diaphragmatic hernia

Experimental study reveals YAP protein dysregulation in nitrofen-induced CDH lung hypoplasia, with increased phosphorylation and cytoplasmic localization compared to normal nuclear expression. Findings suggest Hippo pathway alterations may contribute to abnormal lung development in CDH, offering potential therapeutic targets.