Surgical treatment of congenital hyperinsulinism: Results from 500 pancreatectomies in neonates and children

Large retrospective series of 500 pancreatectomies for congenital hyperinsulinism over 20 years, stratifying outcomes by disease subtype: focal, diffuse, atypical (LINE, Beckwith-Wiedemann), and insulinoma. Study compares surgical approaches—partial resection for focal disease versus near-total pancreatectomy for diffuse disease—and their efficacy in controlling severe neonatal and pediatric hypoglycemia.