Review of Perioperative Prophylactic Antibiotic Use during Laparoscopic Cholecystectomy and Subsequent Surgical Site Infection Development at a Single Children's Hospital

Retrospective study of 502 pediatric patients undergoing elective laparoscopic cholecystectomy found prophylactic antibiotics reduced SSI risk by 77%, though all infections were superficial and low-morbidity. Authors recommend conservative antibiotic use to balance infection prevention against antibiotic resistance concerns.