Preventive effect of prophylactic intravenous antibiotics against cholangitis in biliary atresia: a randomized controlled trial

This randomized trial compared 7-day versus 14-day prophylactic IV antibiotics in 180 biliary atresia patients post-Kasai surgery. While overall 6-month cholangitis rates were similar, extended antibiotics reduced early-onset episodes and frequency, though short-term prophylaxis appears adequate for general protection.