Granulocyte-Colony Stimulating Factor GCSF Mobilizes Hematopoietic Stem Cells in Kasai Patients with Biliary Atresia in a Phase 1 Study and Improves Short Term Outcome

Phase 1 trial demonstrates GCSF safely mobilizes hematopoietic stem cells in infants undergoing Kasai surgery for biliary atresia, with preliminary evidence of improved biliary drainage and reduced cholangitis at 6 months. Study supports advancement to Phase 2 efficacy trial of GCSF as adjunct therapy.