Management and Outcomes for Long-Segment Hirschsprung Disease: A Systematic Review from the APSA Outcomes and Evidence Based Practice Committee

Systematic review by APSA examining long-segment Hirschsprung disease (LSHD), finding no consensus on optimal surgical approach but identifying increased risk of enterocolitis and long-term GI symptoms compared to short-segment disease. Authors recommend standardized anatomic definitions and highlight stem cell therapy as a potential future treatment avenue.