Contemporary Outcomes of the Foker Process and Evolution of Treatment Algorithms for Long-Gap Esophageal Atresia

Space: StayCurrentMD Author: Wendy Jo Svetanoff, Benjamin Zendejas, Kayla Hernandez, Kathryn Davidson, Peter Ngo, Michael Manfredi, Thomas E. Hamilton, Russell Jennings, C. Jason Smithers Published:

Author / Expert

Wendy Jo Svetanoff, Benjamin Zendejas, Kayla Hernandez, Kathryn Davidson, Peter Ngo, Michael Manfredi, Thomas E. Hamilton, Russell Jennings, C. Jason Smithers

Topic overview

Abstract

Background

Esophageal growth using the Foker process (FP) for long-gap esophageal atresia (LGEA) has evolved over time.

Methods

Contemporary LGEA patients treated from 2014–2020 were compared to historical controls (2005 to <2014).

Results

102 contemporary LGEA patients (type A 50%, B 18%, C 32%; 36% prior anastomotic attempt; 20 with esophagostomy) underwent either primary repair (n=23), jejunal interposition (JI; n = 14), or Foker process (FP; n = 65; 49 primary [p], 16 rescue [r]). The contemporary p-FP cohort experienced significantly fewer leaks on traction (4% vs 22%), bone fractures (2% vs 22%), anastomotic leak (12% vs 37%), and Foker failure (FP→JI; 0% vs 15%), when compared to historical p-FP patients (n = 27), all p ≤ 0.01. Patients who underwent a completely (n = 11) or partially (n = 11) minimally invasive FP experienced fewer median days paralyzed (0 vs 8 vs 17) and intubated (9 vs 15 vs 25) compared to open FP patients, respectively (all p ≤ 0.03), with equivalent leak rates (18% vs 9% vs 26%, p = 0.47). At one-year post-FP, most patients (62%) are predominantly orally fed.

Conclusion

With continued experience and technical refinements, the Foker process has evolved with improved outcomes, less morbidity and maximal esophageal preservation.

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