Early Management of Meconium Ileus in Infants with Cystic Fibrosis: A Prospective Population Cohort Study

Prospective UK/Ireland study of 56 CF infants with meconium ileus shows that repeat contrast enemas increased non-operative success rates and reduced time to full feeds compared to surgical intervention. Management approaches varied widely across centers, with 25% requiring primary laparotomy and 4% mortality rate.